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2.A.39.4.2
The nicotinamide riboside transporter, Nrt1 (Belenky et al., 2008)

Accession Number:Q08485
Protein Name:Putative thiamine transporter YOR071C
Length:598
Molecular Weight:67193.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Nicotinamide ribosides

Cross database links:

Genevestigator: Q08485
eggNOG: fuNOG07780
HEGENOM: HBG626339
DIP: DIP-7934N
RefSeq: NP_014714.1   
Entrez Gene ID: 854237   
Pfam: PF02133   
KEGG: sce:YOR071C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0034257 F:nicotinamide riboside transporter activity
GO:0015205 F:nucleobase transmembrane transporter activity
GO:0034258 P:nicotinamide riboside transport
GO:0015888 P:thiamin transport

References (3)

[1] “The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the presence of two tRNAs and 24 new open reading frames.”  Valens M.et.al.   9133743
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[3] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSFSSIVSKF LRYLEIPAKN RTAVNFLRNP DLQPIKSANQ TWGFWSNLAY WGAVSFTAGT 
61:	WMSGSAALSV GLSYPETIVS FLLGNVLTII FTMANSYPGY DWKIGFTLAQ RFVFGIYGSA 
121:	FGIIIRILMS IVNYGSNAWL GGLSINMILD SWSHHYLHLP NTLSPSVAMT TKQLVGFIIF 
181:	HVLTALCYFM KPYHMNYLLI WSCVATCFAM LGIVIYLTKN AHGVGELFTS TKSTVTGSKR 
241:	AWAWVYMISY WFGSISPGST NQSDYSRFGS SNLAIWTGSV CALLIPATLV PIFGVISAST 
301:	CDKLYGKQFW MPMDIFDYWL TNNYSAGARA GAFFCGLCFT MSQMSSTISN CGFATGMDMA 
361:	GLLPKYVDIK RGALFCACIS WACLPWNFYN SSSTFLTVMS SFGVVMTPII AVMICDNFLI 
421:	RKRQYSITNA FILKGEYYFT KGVNWRAIVA WVCGMAPGLP GIAWEVNNNY FHDSGIVKFF 
481:	YGDSFFSFLI SFFVYWGLCV FFPFKITVRH DDKDYYGAFT DEEARKKGMI PYSEISEEEI 
541:	RAYTLGECYT TGHEYKPESS DNESPELIKT SSENTNVFEI VHQKDDEKHS FSTTQQVV