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2.A.4.1.6
Mitochondrial metal transporter 2

Accession Number:Q08970
Protein Name:Mitochondrial metal transporter 2
Length:484
Molecular Weight:52434.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate Metal ions

Cross database links:

Genevestigator: Q08970
eggNOG: COG0053
HEGENOM: HOG000174851
DIP: DIP-3963N
Entrez Gene ID: 855877   
Pfam: PF01545   
KEGG: sce:YPL224C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0031966 C:mitochondrial membrane
GO:0005739 C:mitochondrion
GO:0008324 F:cation transmembrane transporter activity
GO:0006879 P:cellular iron ion homeostasis

References (3)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.”  Bussey H.et.al.   9169875
[2] “Characterization of two homologous yeast genes that encode mitochondrial iron transporters.”  Li L.et.al.   9353309
[3] “The proteome of Saccharomyces cerevisiae mitochondria.”  Sickmann A.et.al.   14576278

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLRISIDSIK QFGSFVPGYN NTSYHAAGRA IRTSSLYSTM ISANPRRCLH SSKLLNKEGQ 
61:	EEGYNEQLIS KMSSQNGSNS RQNESEGKKE GKASSVKSLL QHTHSHSHTH MHDNPLLSLN 
121:	VQQIKKNPGV RITWIGLASN VGMAVGKFVG GITFHSQALL ADSVHALSDL VSDFLTLFSV 
181:	QYASRKPTSE YPYGYGKVET VGSLAVSTIL AMAGISIGWS SLCAIVGPVI PHAILESMAG 
241:	LIGETHSHSQ SLTQQATNVN AVWIAAGSIL VKEWVFQATK KVAIQTNSNV LMANAWHHRV 
301:	DSLTSLVALV AITSSYFFNI QSLDNLGGLV VSGLIIKTGG QGILSSLKEL VDQSIPPTDP 
361:	RYLEIESVIK DSIGSLKTDL DLKQSLHVRD LTILASGPNL RATTTLEVPV LHSGQEVGIR 
421:	FLENAISTIR EDLRMKVPNV GKVDVEFVDV TSDSKGDLEH SHDTKSTNHT HTHSDSADTH 
481:	THKH