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2.A.40.3.1
Xanthine permease

Accession Number:P42086
Protein Name:PbuX aka XanP
Length:438
Molecular Weight:46238.00
Species:Bacillus subtilis [1423]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Xanthine

Cross database links:

HEGENOM: HBG470187
RefSeq: NP_390088.1   
Entrez Gene ID: 939068   
Pfam: PF00860   
KEGG: bsu:BSU22060   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (3)

[1] “Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism.”  Christiansen L.C.et.al.   9098051
[2] “Organization of the Bacillus subtilis 168 chromosome between kdg and the attachment site of the SP beta prophage: use of long accurate PCR and yeast artificial chromosomes for sequencing.”  Capuano V.et.al.   8969496
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRNGFGKTLS LGIQHVLAMY AGAIVVPLIV GKAMGLTVEQ LTYLVSIDIF MCGVATLLQV 
61:	WSNRFFGIGL PVVLGCTFTA VSPMIAIGSE YGVSTVYGSI IASGILVILI SFFFGKLVSF 
121:	FPPVVTGSVV TIIGITLMPV AMNNMAGGEG SADFGDLSNL ALAFTVLSII VLLYRFTKGF 
181:	IKSVSILIGI LIGTFIAYFM GKVQFDNVSD AAVVQMIQPF YFGAPSFHAA PIITMSIVAI 
241:	VSLVESTGVY FALGDLTNRR LTEIDLSKGY RAEGLAVLLG GIFNAFPYTA FSQNVGLVQL 
301:	TGIKKNAVIV VTGVILMAFG LFPKIAAFTT IIPSAVLGGA MVAMFGMVIA YGIKMLSRID 
361:	FAKQENLLIV ACSVGLGLGV TVVPDIFKQL PSALTLLTTN GIVAGSFTAV VLNIVYNVFS 
421:	KAKKIEQEAD LAEQKTAV