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2.A.43.2.7
Probable vacuolar (lysosomal) cationic amino acid exporter, RTC2 (Ypq3; Ybr147). Involved in amino acid homeostasis. Up-regulated by addition of ammonia or amino acids to a nitrogen-depleted medium (Jézégou et al. 2012). Resistant to fluconazole. Increased resistance to caspofungin. Suppresses CDC13-1 temperature sensitivity.

Accession Number:P38279
Protein Name:Protein RTC2
Length:296
Molecular Weight:33497.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate Cationic amino acids

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FASTA formatted sequence
1:	MKLIPIILNA KNLSGMAGSI SICCWIVVFV PQIYENFRRQ SAEGLSLLFI VLWLLGDIFN 
61:	VMGAMMQNLL PTMIILAAYY TLADLILLIQ CMWYDKEKKS ILQEVKKNVD PVHLPPANPI 
121:	NETVLQDVFN EYEPLLPRIE EEDSQSYSSL ELGRTIVVKE RENFFNDFLI VSGVLIAGIL 
181:	SWYISYCSGL DNGIPKKKPA FEQINLPAQI LGYLSAILYL GSRIPQIVLN FKRKSCEGVS 
241:	FLFFLFACLG NTSFIISVLS ASWLIGSAGT LLMDFTVFIQ FFLYAKPKYE KILIDN