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2.A.45.1.1
Arsenical resistance efflux pump (exports As(III) and Sb(III) probably as polymers of the hydroxides using an H+ antiport mechanism) (Meng et al., 2004)

Accession Number:P30329
Protein Name:ArsB
Length:429
Molecular Weight:46484.00
Species:Staphylococcus aureus [1280]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate As3+, Sb3+, H+

Cross database links:

Pfam: PF02040   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015105 F:arsenite transmembrane transporter activity
GO:0046685 P:response to arsenic
GO:0006810 P:transport

References (1)

[1] “Regulation and expression of the arsenic resistance operon from Staphylococcus aureus plasmid pI258.”  Ji G.et.al.   1534328

External Searches:

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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTILAIVIFL LTLTFVIWQP KGLDIGITAL IGAVVAIITG VVSLSDVLEV TGIVWNATLT 
61:	FVAVILISLI LDEIGFFEWS AIHMVKASNG NGLKMFVFIM LLGAIVAAFF ANDGAALILT 
121:	PIVLAMVRNL GFNQKVIFPF IIASGFIADT TSLPLIVSNL VNIVSADYFD IGFIEYFSRM 
181:	IIPNIFSLIA SILVLWLYFR KSIPKTFDTE NLSDPKSAIK DSKLFKLSWI VLAVLLVGYL 
241:	VSEFIQIPVS IIAGIIAFIF VILARKSKAV HTKQVIKGAP WNIVVFSIGM YLVVFGLKNV 
301:	GITTILGDVL TNISNYGLFS SIMGMGFIAA FLSSIMNNMP TVLIDAIAIG QSSATGILKE 
361:	GMVYANVIGS DLGPKITPIG SLATLLWLHV LTQKGVKISW GTYFKTGIII TIPVLFVTLL 
421:	GLYLTLIIF