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2.A.50.1.2
Protein-cysteine N-palmitoyltransferase HHAT-like protein (Glycerol uptake/transporter homologue) (Hedgehog acyltransferase-like protein)

Accession Number:Q9D1G3
Protein Name:Protein-cysteine N-palmitoyltransferase HHAT-like protein
Length:503
Molecular Weight:56431.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate glycerol

Cross database links:

Genevestigator: Q9D1G3 Q9D1G3
eggNOG: COG1696 COG1696
HEGENOM: HOG000112894 HOG000112894
Entrez Gene ID: 74770    74770   
Pfam: PF03062    PF03062   
KEGG: mmu:74770    mmu:74770   

Gene Ontology

GO:0005783 C:endoplasmic reticulum
GO:0005789 C:endoplasmic reticulum membrane
GO:0016021 C:integral to membrane
GO:0048471 C:perinuclear region of cytoplasm
GO:0060262 P:negative regulation of N-terminal protein palmitoylation
GO:0005783 C:endoplasmic reticulum
GO:0005789 C:endoplasmic reticulum membrane
GO:0016021 C:integral to membrane
GO:0048471 C:perinuclear region of cytoplasm
GO:0060262 P:negative regulation of N-terminal protein palmitoylation

References (6)

[1] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “Mammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehog.”  Abe Y.et.al.   18081866
[4] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[6] “Mammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehog.”  Abe Y.et.al.   18081866

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MGIKTALPAA ELGLYSLVLS GALAYAGRGL LEASQDGAHR KAFRESVRPG WEYLGRKMDV 
61:	ADFEWVMWFT NFRNVIVFAL SGHVLFAKLC TMVAPQLRSW MYAVYGVLAV VGTMGPWYLL 
121:	LLLGHCMVLY VASLLGQRWL CLALGLASLA SFKVDPGISW QSGFVTGTFD LQDVLFHGGS 
181:	SFTVLRCTSF ALESCAHPDR RYSLADLLKY NFYLPFFFFG PIMTFDRFHA QVSQEPVRPE 
241:	GELWHIQAQA GLSAAAIVAV DVFFHFFYIL TIPSDLKFAS RLPDSALAGL AYSNLVYDWV 
301:	KAAVLFGVVN TVARLDHLDP PQPPKCITAL YVFGETHFDR GINDWLCKYV YDHIGGDHST 
361:	VIPELAASVA TFVVTTLWLG PCDIVYLWSV LNCFGLNFEL WVQKLAERGP LAQIEARLSE 
421:	QMSRRVRALC GAVNFWAIIM YNLVSLNSLE FTELVARRLI LTGFPQTTLA VLFVTYCGVQ 
481:	LVKERERSLA LEEEQRQDRE KLE