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2.A.54.1.1
Mitochondrial serine (and possibly cystine and alanine) carrier, Sideroflexin-1 (SFXN1) of 322 aas and possibly 6 TMSs (Kory et al. 2018). This system is believed to be required for one-carbon metabolism because serine is converted into glycine and formate in the mitochondrion. 

Accession Number:Q9H9B4
Protein Name:Sideroflexin-1
Length:322
Molecular Weight:35619.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate Tricarboxylates

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGELPPNIN IKEPRWDQST FIGRANHFFT VTDPRNILLT NEQLESARKI VHDYRQGIVP 
61:	PGLTENELWR AKYIYDSAFH PDTGEKMILI GRMSAQVPMN MTITGCMMTF YRTTPAVLFW 
121:	QWINQSFNAV VNYTNRSGDA PLTVNELGTA YVSATTGAVA TALGLNALTK HVSPLIGRFV 
181:	PFAAVAAANC INIPLMRQRE LKVGIPVTDE NGNRLGESAN AAKQAITQVV VSRILMAAPG 
241:	MAIPPFIMNT LEKKAFLKRF PWMSAPIQVG LVGFCLVFAT PLCCALFPQK SSMSVTSLEA 
301:	ELQAKIQESH PELRRVYFNK GL