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2.A.54.1.5
Sideroflexin-5

Accession Number:Q925N0
Protein Name:Sideroflexin-5
Length:342
Molecular Weight:37329.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate Fe3+

Cross database links:

Genevestigator: Q925N0
eggNOG: NOG283056
HEGENOM: HOG000203440
Entrez Gene ID: 94282   
Pfam: PF03820   
KEGG: mmu:94282   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0008324 F:cation transmembrane transporter activity
GO:0055072 P:iron ion homeostasis

References (2)

[1] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[2] “A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice.”  Fleming M.D.et.al.   11274051

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MADTATTASA ASAAASAPNA STDAPPFQLG KPRFQQTSFY GRFRHFLDII DPRTLFVTEK 
61:	RLREAVQLLE DYKHGTLRPG VTNEQLWSAQ KIKQAILHPD TNEKIFMPFR MSGYIPFGTP 
121:	IVVGLLLPNQ TLASTVFWQW LNQSHNACVN YANRNATKPS PASKFIQGYL GAVISAVSIA 
181:	VGLNVLVQKA NKFTPATRLL VQRFVPFPAV ASANICNVVL MRYGELEEGI DVLDADGNLV 
241:	GSSKIAARHA LLETALTRVV LPMPILVLPP IVMSMLEKTA LLQARPRLLL PVHSLVCLAA 
301:	FGLALPLAIS LFPQMSEIET SQLEPEIARA TSSRTVVYNK GL