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2.A.59.1.2
ArsB arsenite/antimonite exporter (Sato and Kobayashi, 1998)

Accession Number:P45946
Protein Name:ArsB aka yqcL
Length:346
Molecular Weight:38312.00
Species:Bacillus subtilis [1423]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate arsenite, antimonite

Cross database links:

HEGENOM: HBG519064
RefSeq: NP_390456.2   
Entrez Gene ID: 937800   
Pfam: PF01758   
KEGG: bsu:BSU25790   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008508 F:bile acid:sodium symporter activity
GO:0046685 P:response to arsenic
GO:0006814 P:sodium ion transport

References (6)

[1] “Complete nucleotide sequence of a skin element excised by DNA rearrangement during sporulation in Bacillus subtilis.”  Takemaru K.et.al.   7704261
[2] “Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes.”  Mizuno M.et.al.   8969508
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706
[5] “Analysis of a Bacillus subtilis genome fragment using a co-operative computer system prototype.”  Medigue C.et.al.   7489895
[6] “The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite.”  Sato T.et.al.   9537360

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKRLSFLDRY LTIWIFLAMA LGIGLGFIFP SFVGGLNKLQ VGTTSIPLAI GLVLMMYPPL 
61:	AKVRYEEIGR VFKDIKVLIL SLVQNWIIGP TLMFILAIIF LPDKPEYMIG LIMIGLARCI 
121:	AMVIVWNDLS KGDTEYAAGL VAFNSIFQML FFSVYAYIFV TVIPQWLGME GAVVNITMAE 
181:	VAKSVFIYLG VPFIAGMVTR YIFVKVKGKE WYEKVFIPKI SPITLIALLF TIIVMFSLKG 
241:	DVIVSLPLDV VRVAIPLLIY FVLMFFVSFF LGKKIGANYA VTTTLAFTAG SNNFELAIAV 
301:	AVGVFGIHSG AAFAAVIGPL VEVPVMIALV KVALWFQRKY FGSHSM