TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.66.1.5
Ethionine resistance protein, ERC1

Accession Number:P38767
Protein Name:YHJ2 aka ERC1 aka YHR032w
Length:581
Molecular Weight:64209.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ethionine

Cross database links:

Genevestigator: P38767
eggNOG: fuNOG04680
HEGENOM: HBG398292
DIP: DIP-1785N
RefSeq: NP_011897.1   
Entrez Gene ID: 856427   
Pfam: PF01554   
KEGG: sce:YHR032W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015297 F:antiporter activity
GO:0015238 F:drug transmembrane transporter activity
GO:0006855 P:drug transmembrane transport

References (2)

[1] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.”  Johnston M.et.al.   8091229
[2] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSKQFSHTTN DRRSSIIYST SVGKAGLFTP ADYIPQESEE NLIEGEEQEG SEEEPSYTGN 
61:	DDETEREGEY HSLLDANNSR TLQQEAWQQG YDSHDRKRLL DEERDLLIDN KLLSQHGNGG 
121:	GDIESHGHGQ AIGPDEEERP AEIANTWESA IESGQKISTT FKRETQVITM NALPLIFTFI 
181:	LQNSLSLASI FSVSHLGTKE LGGVTLGSMT ANITGLAAIQ GLCTCLDTLC AQAYGAKNYH 
241:	LVGVLVQRCA VITILAFLPM MYVWFVWSEK ILALMIPERE LCALAANYLR VTAFGVPGFI 
301:	LFECGKRFLQ CQGIFHASTI VLFVCAPLNA LMNYLLVWND KIGIGYLGAP LSVVINYWLM 
361:	TLGLLIYAMT TKHKERPLKC WNGIIPKEQA FKNWRKMINL AIPGVVMVEA EFLGFEVLTI 
421:	FASHLGTDAL GAQSIVATIA SLAYQVPFSI SVSTSTRVAN FIGASLYDSC MITCRVSLLL 
481:	SFVCSSMNMF VICRYKEQIA SLFSTESAVV KMVVDTLPLL AFMQLFDAFN ASTAGCLRGQ 
541:	GRQKNRWVHQ PSRILLPRCA HGICVSIPVS SGCRRLMVGY N