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2.A.7.25.2 The nonimprinted in Prader-Willi/Angelman syndrom, subtype 2, NIPA2 protein (360 aas; 9TMSs, 43% identical with NIPA1) Mg²⁺ transport is electrogenic, voltage dependent, and saturable, a K_Mof 0.31mM (very selective for Mg²⁺). (Goytain et al. 2008)
Accession Number:	Q8N8Q9
Protein Name:	NIPA2
Length:	360
Molecular Weight:	39185.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	8
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²

Genevestigator:	Q8N8Q9
eggNOG:	prNOG08258
HEGENOM:	HBG390220
RefSeq:	NP_001008860.1 NP_001008892.1 NP_001008894.1 NP_112184.4
Entrez Gene ID:	81614
Pfam:	PF05653
OMIM:	608146 gene
KEGG:	hsa:81614
Gene Ontology GO:0005769 C:early endosome GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0006811 P:ion transport
References (3) [1] “Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.” Chai J.-H.et.al. 14508708 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334

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CDD Search (Conserved Domain Database)
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FASTA formatted sequence

1:	MSQGRGKYDF YIGLGLAMSS SIFIGGSFIL KKKGLLRLAR KGSMRAGQGG HAYLKEWLWW 
61:	AGLLSMGAGE VANFAAYAFA PATLVTPLGA LSVLVSAILS SYFLNERLNL HGKIGCLLSI 
121:	LGSTVMVIHA PKEEEIETLN EMSHKLGDPG FVVFATLVVI VALILIFVVG PRHGQTNILV 
181:	YITICSVIGA FSVSCVKGLG IAIKELFAGK PVLRHPLAWI LLLSLIVCVS TQINYLNRAL 
241:	DIFNTSIVTP IYYVFFTTSV LTCSAILFKE WQDMPVDDVI GTLSGFFTII VGIFLLHAFK 
301:	DVSFSLASLP VSFRKDEKAM NGNLSNMYEV LNNNEESLTC GIEQHTGENV SRRNGNLTAF

2.A.7.25.2
The nonimprinted in Prader-Willi/Angelman syndrom, subtype 2, NIPA2 protein (360 aas; 9TMSs, 43% identical with NIPA1) Mg²⁺ transport is electrogenic, voltage dependent, and saturable, a K_Mof 0.31mM (very selective for Mg²⁺). (Goytain et al. 2008)

Cross database links:

Gene Ontology

References (3)

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2.A.7.25.2The nonimprinted in Prader-Willi/Angelman syndrom, subtype 2, NIPA2 protein (360 aas; 9TMSs, 43% identical with NIPA1) Mg2+ transport is electrogenic, voltage dependent, and saturable, a KM of 0.31mM (very selective for Mg2+). (Goytain et al. 2008)

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.7.25.2
The nonimprinted in Prader-Willi/Angelman syndrom, subtype 2, NIPA2 protein (360 aas; 9TMSs, 43% identical with NIPA1) Mg²⁺ transport is electrogenic, voltage dependent, and saturable, a K_Mof 0.31mM (very selective for Mg²⁺). (Goytain et al. 2008)