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2.A.8.1.1
D-Gluconate:H+ symporter of 448 aas and 11 TMSs.  It is encoded in an operon with gluconate kinase (Fujita et al. 1986).

Accession Number:P12012
Protein Name:GntP
Length:448
Molecular Weight:46655.00
Species:Bacillus subtilis [1423]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Gluconate

Cross database links:

HEGENOM: HBG649941
RefSeq: NP_391887.1   
Entrez Gene ID: 937715   
Pfam: PF02447   
KEGG: bsu:BSU40070   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015128 F:gluconate transmembrane transporter activity
GO:0019521 P:D-gluconate metabolic process
GO:0015725 P:gluconate transport

References (3)

[1] “Organization and transcription of the gluconate operon, gnt, of Bacillus subtilis.”  Fujita Y.et.al.   3020045
[2] “Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome between the gnt and iol operons.”  Yoshida K.et.al.   7584049
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPLIIVALGI LALLFLIMGL KLNTFISLLV VSFGVALALG MPFDKVVSSI EAGIGGTLGH 
61:	IALIFGLGAM LGKLIADSGG AQRIAMTLVN KFGEKNIQWA VVIASFIIGI ALFFEVGLVL 
121:	LIPIVFAISR ELKISILFLG IPMVAALSVT HGFLPPHPGP TAIAGEYGAN IGEVLLYGFI 
181:	VAVPTVLIAG PLFTKFAKKI VPASFAKNGN IASLGTQKTF NLEETPGFGI SVFTAMLPII 
241:	IMSVATIIDL LQETIGFADN GVLAFIRLIG NASTAMIISL LVAVYTMGIK RNIPVKTVMD 
301:	SCSTAISQIG MMLLIIGGGG AFKQVLINGG VGDYVADLFK GTALSPIILA WLIAAILRIS 
361:	LGSATVAALS TTGLVIPLLG HSDVNLALVV LATGAGSVIA SHVNDAGFWM FKEYFGLSMK 
421:	ETFATWTLLE TIISVAGLGF ILLLSLVV