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2.A.92.1.3
solute carrier family 44, member 3

Accession Number:Q8N4M1
Protein Name:Choline transporter-like protein 3
Length:653
Molecular Weight:73783.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q8N4M1 Q8N4M1
eggNOG: NOG310633 NOG310633
HEGENOM: HOG000231655 HOG000231655
Entrez Gene ID: 126969   
Pfam: PF04515   
KEGG: hsa:126969    hsa:126969   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055085 P:transmembrane transport

References (12)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[5] “An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.”  O'Regan S.et.al.   10677542
[6] “Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.”  Varela I.et.al.   21248752
[7] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[8] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[9] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[10] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[11] “An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.”  O'Regan S.et.al.   10677542
[12] “Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.”  Varela I.et.al.   21248752

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHCLGAEYLV SAEGAPRQRE WRPQIYRKCT DTAWLFLFFL FWTGLVFIMG YSVVAGAAGR 
61:	LLFGYDSFGN MCGKKNSPVE GAPLSGQDMT LKKHVFFMNS CNLEVKGTQL NRMALCVSNC 
121:	PEEQLDSLEE VQFFANTSGS FLCVYSLNSF NYTHSPKADS LCPRLPVPPS KSFPLFNRCV 
181:	PQTPECYSLF ASVLINDVDT LHRILSGIMS GRDTILGLCI LALALSLAMM FTFRFITTLL 
241:	VHIFISLVIL GLLFVCGVLW WLYYDYTNDL SIELDTEREN MKCVLGFAIV STGITAVLLV 
301:	LIFVLRKRIK LTVELFQITN KAISSAPFLL FQPLWTFAIL IFFWVLWVAV LLSLGTAGAA 
361:	QVMEGGQVEY KPLSGIRYMW SYHLIGLIWT SEFILACQQM TIAGAVVTCY FNRSKNDPPD 
421:	HPILSSLSIL FFYHQGTVVK GSFLISVVRI PRIIVMYMQN ALKEQQHGAL SRYLFRCCYC 
481:	CFWCLDKYLL HLNQNAYTTT AINGTDFCTS AKDAFKILSK NSSHFTSINC FGDFIIFLGK 
541:	VLVVCFTVFG GLMAFNYNRA FQVWAVPLLL VAFFAYLVAH SFLSVFETVL DALFLCFAVD 
601:	LETNDGSSEK PYFMDQEFLS FVKRSNKLNN ARAQQDKHSL RNEEGTELQA IVR