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3.A.1.106.7
The Salmochelin/Enterobactin secretory exporter, IroC (Crouch et al., 2008; Müller et al. 2009).

Accession Number:Q8RMB7
Protein Name:IroC
Length:1218
Molecular Weight:131874.00
Species:Salmonella choleraesuis GN=iroC PE=3 SV=1 [28901]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Salmochelin, Enterochelin

Cross database links:

HEGENOM: HBG429047
RefSeq: YP_217692.1   
Entrez Gene ID: 3335207   
Pfam: PF00664    PF00005   
BioCyc: SENT321314:SCH_2705-MONOMER   
KEGG: sec:SC2705   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (2)

[1] “Cloning and characterization of an iron regulated locus, iroA, in Salmonella enterica serovar Choleraesuis.”  Wu W.S.et.al.   12652904
[2] “The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.”  Chiu C.-H.et.al.   15781495

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPATHSPMPA RAWIVRLARV CWERKTLSII VIVASVSTIL LAALTPLITR QAVNDAIAGD 
61:	TTHLPLLACG LLLIALFDFI GNYVRRGYAG ELSLWVQHTL RSRAFDSIQK LDGAGQDALR 
121:	TGQVISRTNS DLQQVHTLLQ MCPVPMAVLT YYVAGIAVML WMSPSMTLIV ICVLAALAIT 
181:	ALRARRRVFA QTGLASDRLA HMTEHMREVL EQISVVKSCV AELRETRWLD GQSRQMVRVR 
241:	IGAAISQAMP GATMLALPVI GQIVLLCYGG WSVMNGRIDL GTFVAFASFL AMLTGPTRVL 
301:	ASFLVIAQRT QASVERVFAL IDTRSRMEDG TESVEGQIIG LDVEKMSFHY DNGNRILNEI 
361:	SFSIHAGETV AVVGASGSGK STLLMLLARF YDPTSGGVWL NTTTGQQNIR DLKLTALRRR 
421:	VGVVFEDAFL FAGTVAENIA YGHPQATQDD IRRAADAAGA SGFINALPQG FNTRLTERGS 
481:	NLSGGQRQRI ALARALITAP ELLILDDTTS AVDAGTEAEI NTALGRYADN EHMLLVIARR 
541:	RSTLQLADRI VVLDKGRVVD IGTQAELDAR CPTFRSLMSG EGDFLALAPA EQRTLWPTTQ 
601:	AVKSDDAHER QTPAGKGFVD RMTRVPERAV QMALAGHGRQ VSSLLTPVAW MFVIAALLIA 
661:	LDSAAGVGVL VLLQRGIDSG VAAGDMSTIG ICALLALCLV AIGWCCYALQ TIFAARAAES 
721:	VQHTVRLRSF SHLLRLSLPW HEKHIDSRLT RMTVDVDSLA RFLQNGLASA ATSIVTMVAI 
781:	AAAMFWLDPI LALTALSAVP VVMLATWIYR RLSSPAYAQA RLEIGKVNST LQEKVSGMRV 
841:	VQSHGQQKQE AARLRALSDN FRATRVRAQK YLAVYFPFLT FCTEAAYAAV LLIGATRVAG 
901:	GEMTPGILAA FFLLLGQFYG PVQQLSGIVD SWQQATASGK HINALLATED TENIEPSSIT 
961:	PGTGGALRLE ALTFRYPEKT QPVLDKLSLT IPPGTVVAVV GRSGAGKSTL IKLLAGLYSP 
1021:	GSGQIRVGER LIDAASLSDY RRQTGLVTQD VALFSGDIAE NIRYPRPNSS DTEVESAARR 
1081:	AGLFETVQHL PLGFRTPVNN GGTDLSAGQR QLIALARAHL AQAHILLLDE ATARIDRSAE 
1141:	ERLMTSLTRV THTEKRIALI VAHRLTTARR CDVIVVIDKG CIAEYGSHEQ LIATHGLYAR 
1201:	LWRDSIGQTR DTQGEVIG