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3.A.1.11.1
Polyamine (putrescine/spermidine) uptake porter.  Plays a role in biofilm formation (Zhang et al. 2013).  Spermidine-preferring (Igarashi and Kashiwagi 1996).

Accession Number:P69874
Protein Name:Spermidine/putrescine import ATP-binding protein PotA aka B1126
Length:378
Molecular Weight:43028.00
Species:Escherichia coli [83333]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate Spermidine, Putrescine

Cross database links:

RefSeq: AP_001752.1    NP_415644.1   
Entrez Gene ID: 946323   
Pfam: PF00005    PF08402   
BioCyc: EcoCyc:POTA-MONOMER    ECOL168927:B1126-MONOMER   
KEGG: ecj:JW1112    eco:b1126   

Gene Ontology

GO:0043190 C:ATP-binding cassette (ABC) transporter complex
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0015417 F:polyamine-transporting ATPase activity
GO:0005515 F:protein binding
GO:0015846 P:polyamine transport

References (9)

[1] “Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.”  Furuchi T.et.al.   1939142
[2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.”  Oshima T.et.al.   8905232
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Spermidine-preferential uptake system in Escherichia coli. ATP hydrolysis by PotA protein and its association with membranes.”  Kashiwagi K.et.al.   7592703
[6] “Isolation of polyamine transport-deficient mutants of Escherichia coli and cloning of the genes for polyamine transport proteins.”  Kashiwagi K.et.al.   2249996
[7] “Functions of potA and potD proteins in spermidine-preferential uptake system in Escherichia coli.”  Kashiwagi K.et.al.   8366082
[8] “Transcriptional inhibition of the operon for the spermidine uptake system by the substrate-binding protein PotD.”  Antognoni F.et.al.   9890949
[9] “The ATPase activity and the functional domain of PotA, a component of the spermidine-preferential uptake system in Escherichia coli.”  Kashiwagi K.et.al.   11976340

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGQSKKLNKQ PSSLSPLVQL AGIRKCFDGK EVIPQLDLTI NNGEFLTLLG PSGCGKTTVL 
61:	RLIAGLETVD SGRIMLDNED ITHVPAENRY VNTVFQSYAL FPHMTVFENV AFGLRMQKTP 
121:	AAEITPRVME ALRMVQLETF AQRKPHQLSG GQQQRVAIAR AVVNKPRLLL LDESLSALDY 
181:	KLRKQMQNEL KALQRKLGIT FVFVTHDQEE ALTMSDRIVV MRDGRIEQDG TPREIYEEPK 
241:	NLFVAGFIGE INMFNATVIE RLDEQRVRAN VEGRECNIYV NFAVEPGQKL HVLLRPEDLR 
301:	VEEINDDNHA EGLIGYVRER NYKGMTLESV VELENGKMVM VSEFFNEDDP DFDHSLDQKM 
361:	AINWVESWEV VLADEEHK