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3.A.1.110.2
Colicin V exporter. The ATPase is a GTPase (Zhong and Tai 1998; ).

Accession Number:P22520
Protein Name:CvaB
Length:698
Molecular Weight:78246.00
Species:Escherichia coli [562]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Colicin V

Cross database links:

RefSeq: YP_002539301.1   
Entrez Gene ID: 7379489   
Pfam: PF00664    PF00005    PF03412   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0008234 F:cysteine-type peptidase activity
GO:0043213 P:bacteriocin transport
GO:0006508 P:proteolysis
GO:0055085 P:transmembrane transport

References (2)

[1] “Genetic analysis of an MDR-like export system: the secretion of colicin V.”  Gilson L.et.al.   2249654
[2] “Characterization of a hemoglobin protease secreted by the pathogenic Escherichia coli strain EB1.”  Otto B.R.et.al.   9743528

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MTNRNFRQII NLLDLRWQRR VPVIHQTETA ECGLACLAMI CGHFGKNIDL IYLRRKFNLS 
61:	ARGATLAGIN GIAEQLGMAT RALSLELDEL RVLKTPCILH WDFSHFVVLV SVKRNRYVLH 
121:	DPARGIRYIS REEMSRYFTG VALEVWPGSE FQSETLQTRI SLRSLINSIY GIKRTLAKIF 
181:	CLSVVIEAIN LLMPVGTQLV MDHAIPAGDR GLLTLISAAL MFFILLKAAT STLRAWSSLV 
241:	MSTLINVQWQ SGLFDHLLRL PLAFFERRKL GDIQSRFDSL DTLRATFTTS VIGFIMDSIM 
301:	VVGVCVMMLL YGGYLTWIVL CFTTIYIFIR LVTYGNYRQI SEECLVREAR AASYFMETLY 
361:	GIATVKIQGM VGIRGAHWLN MKIDAINSGI KLTRMDLLFG GINTFVTACD QIVILWLGAG 
421:	LVIDNQMTIG MFVAFSSFRG QFSERVASLT SFLLQLRIMS LHNERIADIA LHEKEEKKPE 
481:	IEIVADMGPI SLETNGLSYR YDSQSAPIFS ALSLSVAPGE SVAITGASGA GKTTLMKVLC 
541:	GLFEPDSGRV LINGIDIRQI GINNYHRMIA CVMQDDRLFS GSIRENICGF AEEMDEEWMV 
601:	ECARASHIHD VIMNMPMGYE TLIGELGEGL SGGQKQRIFI ARALYRKPGI LFMDEATSAL 
661:	DSESEHFVNV AIKNMNITRV IIAHRETTLR TVDRVISI