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3.A.1.110.8
Surface layer protein exporter

Accession Number:Q9Z3C5
Protein Name:SapD
Length:583
Molecular Weight:63959.00
Species:Campylobacter fetus [196]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate S-layer Proteins

Cross database links:

Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0030256 C:type I protein secretion system complex
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0008565 F:protein transporter activity
GO:0030253 P:protein secretion by the type I secretion s...
GO:0055085 P:transmembrane transport

References (35)

[1] “Campylobacter fetus surface layer proteins are transported by a type I secretion system.”  Thompson S.A.et.al.   9851986
[2] “Characterization of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains.”  Tummuru M.K.et.al.   1522068
[3] “Rearrangement of sapA homologs with conserved and variable regions in Campylobacter fetus.”  Tummuru M.K.et.al.   8346244
[4] “A lipopolysaccharide-binding domain of the Campylobacter fetus S-layer protein resides within the conserved N terminus of a family of silent and divergent homologs.”  Dworkin J.et.al.   7896695
[5] “Surface array protein of Campylobacter fetus. Cloning and gene structure.”  Blaser M.J.et.al.   2387868
[6] “”  Blaser M.J.et.al.   2229082
[7] “Structure and genotypic plasticity of the Campylobacter fetus sap locus.”  Tu Z.C.et.al.   12694614
[8] “Campylobacter fetus surface layer proteins are transported by a type I secretion system.”  Thompson S.A.et.al.   9851986
[9] “Characterization of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains.”  Tummuru M.K.et.al.   1522068
[10] “Rearrangement of sapA homologs with conserved and variable regions in Campylobacter fetus.”  Tummuru M.K.et.al.   8346244
[11] “A lipopolysaccharide-binding domain of the Campylobacter fetus S-layer protein resides within the conserved N terminus of a family of silent and divergent homologs.”  Dworkin J.et.al.   7896695
[12] “Surface array protein of Campylobacter fetus. Cloning and gene structure.”  Blaser M.J.et.al.   2387868
[13] “”  Blaser M.J.et.al.   2229082
[14] “Structure and genotypic plasticity of the Campylobacter fetus sap locus.”  Tu Z.C.et.al.   12694614
[15] “Campylobacter fetus surface layer proteins are transported by a type I secretion system.”  Thompson S.A.et.al.   9851986
[16] “Characterization of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains.”  Tummuru M.K.et.al.   1522068
[17] “Rearrangement of sapA homologs with conserved and variable regions in Campylobacter fetus.”  Tummuru M.K.et.al.   8346244
[18] “A lipopolysaccharide-binding domain of the Campylobacter fetus S-layer protein resides within the conserved N terminus of a family of silent and divergent homologs.”  Dworkin J.et.al.   7896695
[19] “Surface array protein of Campylobacter fetus. Cloning and gene structure.”  Blaser M.J.et.al.   2387868
[20] “”  Blaser M.J.et.al.   2229082
[21] “Structure and genotypic plasticity of the Campylobacter fetus sap locus.”  Tu Z.C.et.al.   12694614
[22] “Campylobacter fetus surface layer proteins are transported by a type I secretion system.”  Thompson S.A.et.al.   9851986
[23] “Characterization of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains.”  Tummuru M.K.et.al.   1522068
[24] “Rearrangement of sapA homologs with conserved and variable regions in Campylobacter fetus.”  Tummuru M.K.et.al.   8346244
[25] “A lipopolysaccharide-binding domain of the Campylobacter fetus S-layer protein resides within the conserved N terminus of a family of silent and divergent homologs.”  Dworkin J.et.al.   7896695
[26] “Surface array protein of Campylobacter fetus. Cloning and gene structure.”  Blaser M.J.et.al.   2387868
[27] “”  Blaser M.J.et.al.   2229082
[28] “Structure and genotypic plasticity of the Campylobacter fetus sap locus.”  Tu Z.C.et.al.   12694614
[29] “Campylobacter fetus surface layer proteins are transported by a type I secretion system.”  Thompson S.A.et.al.   9851986
[30] “Characterization of the Campylobacter fetus sapA promoter: evidence that the sapA promoter is deleted in spontaneous mutant strains.”  Tummuru M.K.et.al.   1522068
[31] “Rearrangement of sapA homologs with conserved and variable regions in Campylobacter fetus.”  Tummuru M.K.et.al.   8346244
[32] “A lipopolysaccharide-binding domain of the Campylobacter fetus S-layer protein resides within the conserved N terminus of a family of silent and divergent homologs.”  Dworkin J.et.al.   7896695
[33] “Surface array protein of Campylobacter fetus. Cloning and gene structure.”  Blaser M.J.et.al.   2387868
[34] “”  Blaser M.J.et.al.   2229082
[35] “Structure and genotypic plasticity of the Campylobacter fetus sap locus.”  Tu Z.C.et.al.   12694614

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRANEPKISE LKETIKKSKN CIVYAAIFSF FVNLLMLTPP LYMLQLYDRV VTSRSESTLF 
61:	FLTLIVLFLF ITMAIFEILR SRILIVFGNQ IDLNLTDRIY DAIFKLASRV PGRVTSQAMG 
121:	DLNAIKQYMS TNGIFAFLDA PWLPVYIAIL FVFHPWYGWF AIAAAIILFG VALLNEKATK 
181:	DGLKKSNDTY KNEMRLIDMN LRNSEVINAM GMNNNLKKIW KNKHHTFLNS HSDASIKAGV 
241:	YTNISKATRV TSQSMMLGLG AYLVLKMEVS PGMMIAGSIL LGRALAPLDI LIASWKSYKN 
301:	TKESYERLDK FLHDFPVEKD KLSLPDPRGD IACEAISLIP PSAKQPSLIG VSFALDAGDM 
361:	CAIIGPSAAG KSSLARAILG IWPVAHGVVR VDCADINQYY SDALGGFVGY LPQDVELFEG 
421:	TIAENIARFG ELDSVAVVEA AKSANVHDMI LRLPDGYDTK IGLGGMSLSG GQRQRVALAR 
481:	ALYKNPKIIV LDEPNASLDE EGERALYAAL LAMKGKATII LITHKLNVLQ AVDKIAVLNA 
541:	GQLVYFGERD AVLAKLSGNT APATKQVKTA AASISLDDAK EDE