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3.A.1.120.1
Macrolide ATPase (membrane constituent unknown)

Accession Number:Q53762
Protein Name:SrmB
Length:550
Molecular Weight:60147.00
Species:Streptomyces ambofaciens [1889]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Macrolides

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (1)

[1] “Characterization of a novel regulatory gene governing the expression of a polyketide synthase gene in Streptomyces ambofaciens.”  Geistlich M.et.al.   1508047

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSIAQYALHD ITKRYHDCVV LDRVGFSIKP GEKVGVIGDN GSGKSTLLKI LAGRVEPDNG 
61:	ALTVVAPGGV GYLAQTLELP LDATVQDAVD LALSDLRELE AAMREAEAEL GESDENGSER 
121:	ELSAGLQRYA ALVEQYQARG GYEADVRVEV ALHGLGLPSL DRDRKLGTLS GGERSRLALA 
181:	ATLASSPELL LLDEPTNDLD DRAMEWLEDH LAGHRGTVIA VTHDRVFLDR LTTTILEVDS 
241:	GSVTRYGNGY EGYLTAKAVE RERRLREYEE WRAELDRNRG LITSNVARMD GIPRKMSLSV 
301:	FGHGAYRRRG RDHGAMVRIR NAKQRVAQLT ENPVHAPADP LSFAARIDTA GPEAEEAVAE 
361:	LTDVRVAGRL AVDSLTIRPG ERLLVTGPNG AGKSTLLRVL SGELEPDGGS VRVGCRVGHL 
421:	RQDETPWAPG LTVLRAFAQG REGYLEDHAE KLLSLGLFSP SDLRRRVKDL SYGQRRRIEI 
481:	ARLVSDPMDL LLLDEPTNHL TPVLVEELEQ ALADYRGAVV VVTHDRRMRS RFTGARLTMG 
541:	DGRIAEFSAG