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3.A.1.120.2
Tylosin ATPase (membrane constituent unknown)

Accession Number:P25256
Protein Name:TlrC
Length:548
Molecular Weight:59130.00
Species:Streptomyces fradiae [1906]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Tylosin

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0046677 P:response to antibiotic
GO:0006810 P:transport

References (1)

[1] “Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport.”  Rosteck P.R. Jr.et.al.   1864505

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRTSPSSQLS LHGVTKRYDD RVVLSQVSLA ISPGEKAGII GDNGAGKSTL LRLLAGEERP 
61:	DAGEVTVIAP GGVGYLPQTL GLPPRATVQD AIDLAMTELR VLEAELRRTE AALAEAATDE 
121:	ALQDALTAYA RLTEQYEVRD GYGADARVDA ALHGLGLPGL PRDRRLGTLS GGERSRLALA 
181:	ATLASQPELL LLDEPTNDLD DRAVHWLEEH LSGHRGTVVT VTHDRVFLDR LTATVLEVDG 
241:	RGVSRHGDGY AGYLAAKAAE RRRRQQQYDE WRAELDRNRR LAEANVARLD GIPRKMGKAA 
301:	FGHGAFRARG RDHGAMSRVR NAKERVERLT ANPVAPPADR LSLTARIATA DGPGEAPAAE 
361:	LDGVVVGSRL RVPKLRLGAA ERLLITGPNG AGKSTLLSVL AGELSPDAGA VSVPGRVGHL 
421:	RQEETPWPAK LTVLEAFAHN RPGDRDEQAD RRLSLGLFEP EALRLRVGEL SYGQRRRIEL 
481:	ARLVSEPVGL LLLDEPTNHL SPALVEELEE ALTGYGGALV LVTHDRRMRS RFTGSHLELR 
541:	EGVVSGAR