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3.A.1.204.6 The efflux porter for phosphatidylcholine and its analogues as well as toxic alkyl phospholipids, ABCG4 (Castanys-Munoz et al., 2007). Also promotes cholesterol efflux to the mature forms of HDL (HDL2 and HDL3) (Voloshyna and Reiss, 2011).
Accession Number:	A4HWI7
Protein Name:	ABCG4
Length:	741
Molecular Weight:	83045.00
Species:	Leishmania infantum [5671]
Number of TMSs:	5
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	Phosphatidylcholine, alkyl phospholipids, cholesterol

eggNOG:	KOG0061
HEGENOM:	HBG521184
RefSeq:	XP_001464428.1
Entrez Gene ID:	5067821
Pfam:	PF01061 PF00005
Gene Ontology GO:0016020 C:membrane GO:0005524 F:ATP binding GO:0016887 F:ATPase activity
References (1) [1] “Comparative genomic analysis of three Leishmania species that cause diverse human disease.” Peacock C.S.et.al. 17572675

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FASTA formatted sequence

1:	MGTQVDQAHK PSVGTPTELT SIPPTASVTP PQAKSNAEDA KVPALSRAVN FTWENLTYQV 
61:	PVEDKDGNVI YKTLLFNLSG CAKGGRVLAI MGPSGAGKTT LMGTITGKLF NATARQEGCC 
121:	FMNNNIYQQR YKRLVSYVCQ DDIVMGKDTP REAIYFSARL RLGLDSETAR RRVADVIKRL 
181:	SLTKCQDTIL GIPGILKGVS GGERKRANIG TELVTNPFVM LLDEPTTGLD SVNAVRVGHL 
241:	LQDLAKNDMR TVIATVHSPS SELFDLFDDL LLLAKGHVIY HGPTADSIEY FASLGYDVPP 
301:	RTNPTEYFMN LLQLPEEILS QLWLAWEDYV MSDAANDNPC LTPVTGVITL TDDYLEEQLE 
361:	LKGANFCLQF SELFKRSWRM YLRDPGNFYG RSVQTLFFAI FVGLFFFNLQ LNQQGVQDRL 
421:	GALYVTLMNN LFGAAMNGIA AFPPERAVFL QEQANDAYNA YTYFLAKNLA ELPWQILFPT 
481:	VFDLIAYFMI HFHRSAGAFF VHWFILVLLA NLGYSFGLMF ATFFKQSQAA FAMVPLILLP 
541:	LFIVAGLFAN TDRLYPYWEW LNYISFPRHA YLGVFTNEFE RLTVICDPVT PLCTFPDGQA 
601:	VIEYMGFQGW HYWQTFVALI VYQIGLRFIG ATSLYYQGRQ RRGKLQFVKN LRKRVASPRA 
661:	IASARSNDEL SDVQSTLVGS IATPSNAYGT GVSSPINNPE NHQPIWDGES ERATLALPDT 
721:	PVTYVESPVD VKDMKPRKYR S

3.A.1.204.6
The efflux porter for phosphatidylcholine and its analogues as well as toxic alkyl phospholipids, ABCG4 (Castanys-Munoz et al., 2007). Also promotes cholesterol efflux to the mature forms of HDL (HDL2 and HDL3) (Voloshyna and Reiss, 2011).

Cross database links:

Gene Ontology

References (1)

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Analyze:

3.A.1.204.6The efflux porter for phosphatidylcholine and its analogues as well as toxic alkyl phospholipids, ABCG4 (Castanys-Munoz et al., 2007). Also promotes cholesterol efflux to the mature forms of HDL (HDL2 and HDL3) (Voloshyna and Reiss, 2011).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.A.1.204.6
The efflux porter for phosphatidylcholine and its analogues as well as toxic alkyl phospholipids, ABCG4 (Castanys-Munoz et al., 2007). Also promotes cholesterol efflux to the mature forms of HDL (HDL2 and HDL3) (Voloshyna and Reiss, 2011).