3.A.1.205.28
ABCG30 or PDR2 of 1400 aas and 12 TMSs in a C-M-C-M domain arrangement. Responds to abiotic stresses such as heavy metals (Cd2+, Pb2+, etc), and is regulated by hormones related to pathogenic defenses (Crouzet et al. 2006) . It may be a heavy metal efflux pump, but may also transport abscisic acid, influencing developmental processes, including seed and bud dormancy, the control of organ size and stomatal closure (Lefèvre and Boutry 2018).
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| Accession Number: | Q8GZ52 |
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| Protein Name: | ABC transporter G family member 30 |
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| Length: | 1400 |
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| Molecular Weight: | 157768.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MIQTGEEDEE KATSLEVEFA SGNGVDDEEE LRLQWATVER LPTFKRVTTA LLARDEVSGK
61: GRVIDVTRLE GAERRLLIEM LVKQIEDDNL RLLRKIRKRI DKVGIELPTV EVRFNNLSVE
121: AECQVIHGKP IPTLWNTIKG LLSEFICSKK ETKIGILKGV SGIVRPGRMT LLLGPPGCGK
181: TTLLQALSGK FSDSVKVGGE VCYNGCSLSE FIPEKTSSYI SQNDLHIPEL SVRETLDFSA
241: CCQGIGSRME IMKEISRMEK LQEIIPDPAV DAYMKATSVE GLKNNLQTDY ILKILGLDIC
301: ADTRVGDATR PGISGGEKRR LTTGELVVGP ATTLFMDEIS NGLDSSTTFQ IVSCLQQLAH
361: IAEATILISL LQPAPETFEL FDDVILMGEG KIIYHAPRAD ICRFFEEFGF KCPERKGVAD
421: FLQEIMSKKD QEQYWCHRDK PYSYISVDSF INKFKESNLG LLLKEELSKP FNKSQTRKDG
481: LCYKKYSLGK WEMLKACSRR EFLLMKRNSF IYLFKSALLV FNALVTMTVF LQVGATTDSL
541: HGNYLMGSLF TALFRLLADG LPELTLTISR LGVFCKQKDL YFYPAWAYAI PSIILKIPLS
601: VLDSFIWTLL TYYVIGYSPE VKRFFLQFLI LSTFNLSCVS MFRAIAAIFR TIIASTITGA
661: ISILVLSLFG GFVIPKSSMP AWLGWGFWLS PLSYAEIGLT ANEFFSPRWS KVISSKTTAG
721: EQMLDIRGLN FGRHSYWTAF GALVGFVLFF NALYVLALTY QNNPQRSRAI ISHEKYSRPI
781: EEDFKPCPKI TSRAKTGKII LPFKPLTVTF QNVQYYIETP QGKTRQLLSD ITGALKPGVL
841: TSLMGVSGAG KTTLLDVLSG RKTRGIIKGE IKVGGYPKVQ ETFARVSGYC EQFDIHSPNI
901: TVEESLKYSA WLRLPYNIDS KTKNELVKEV LETVELDDIK DSVVGLPGIS GLSIEQRKRL
961: TIAVELVANP SIIFMDEPTT GLDARAAAIV MRAVKNVAET GRTVVCTIHQ PSIDIFETFD
1021: ELILMKNGGQ LVYYGPPGQN SSKVIEYFES FSGLPKIQKN CNPATWILDI TSKSAEEKLG
1081: IDFSQSYKDS TLYKQNKMVV EQLSSASLGS EALRFPSQFS QTAWVQLKAC LWKQHYSYWR
1141: NPSHNITRIV FILLDSTLCG LLFWQKAEDI NNQQDLISIF GSMYTLVVFP GMNNCAAVIN
1201: FIAAERNVFY RERFARMYSS WAYSFSQVLI EVPYSLLQSL LCTIIVYPTI GYHMSVYKMF
1261: WSLYSIFCSL LIFNYSGMLM VALTPNIHMA VTLRSSFFSM LNLFAGFVIP KQKIPKWWIW
1321: MYYLSPTSWV LEGLLSSQYG DVDKEILVFG EKKRVSAFLE DYFGYKHESL AVVAFVLIAY
1381: PIIVATLFAF FMSKLSFQKK