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3.A.1.208.12
Bile acid transporter, BAT1 (in vacuoles)

Accession Number:P32386
Protein Name:YBT1 aka BAT1 aka YLL048C
Length:1661
Molecular Weight:189162.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:17
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate bile acids

Cross database links:

Genevestigator: P32386
eggNOG: fuNOG05955
HEGENOM: HBG734884
DIP: DIP-6474N
RefSeq: NP_013052.1   
Entrez Gene ID: 850678   
Pfam: PF00664    PF00005   
KEGG: sce:YLL048C   

Gene Ontology

GO:0000324 C:fungal-type vacuole
GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0015125 F:bile acid transmembrane transporter activity
GO:0005515 F:protein binding
GO:0015721 P:bile acid and bile salt transport
GO:0055085 P:transmembrane transport

References (9)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.”  Johnston M.et.al.   9169871
[2] “RNP1, a new ribonucleoprotein gene of the yeast Saccharomyces cerevisiae.”  Cusick M.E.et.al.   8139928
[3] “A yeast ATP-binding cassette-type protein mediating ATP-dependent bile acid transport.”  Ortiz D.F.et.al.   9182565
[4] “Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.”  Ficarro S.B.et.al.   11875433
[5] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[6] “Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.”  Gruhler A.et.al.   15665377
[7] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.”  Li X.et.al.   17330950
[8] “Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.”  Smolka M.B.et.al.   17563356
[9] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MHHVLNSTRP DHRFWFYDDV TQYGRTKYLN YYTPLVLLIF TVLFITYNIW KHYYYYDVLH 
61:	LKQKNPIDEL LYSSTDEDEQ SPLINNNTIT TNYVDNNCTK DALKNRHFSL EKLKSVKVNG 
121:	EPHGTPEIVR RGFIEKSRII LEFFLVLSQV IIHSFILLHY VNKNPEFTQQ GTITGLVEWC 
181:	ALFIIVSLRL ANVNQNFKFI NKYPGNLWSV SFINYLALFI SMILPFRSIF IHHINSPISR 
241:	KYYISQISIN LALFLLLFFA RIRNNFAIIY KTDSWITPSP EPVTSIAGFI CWAWLDSFVW 
301:	KAHKVSIKVK DIWGLMMQDY SFFVVKKFRY FVDHKVKRKR IFSLNLFFFF SNYLVLQCFW 
361:	AFLGSVLSFI PTVLLKRILE YVEDQSSAPS NLAWFYVTVM FVGRILVAIC QAQALFFGRR 
421:	VCIRMKSIII SEIYTKALRR KISTNKTKPS NEDPQEINDQ KSINGDEEST SSANLGAIIN 
481:	LMAIDAFKVS EICGYLHSFL EAFVMTVVAL ALLYRLLGFA AIVGVLIIVA MLPLNYKLAK 
541:	YIGDLQKKNL AVTDNRIQKL NEAFQAIRII KYFSWEENFE KDINTIRENE LSLLLMRSIV 
601:	WSISSFLWFV TPTIVTAASF AYYIYVQGEV LTTPVAFTAL SLFTLLRDPL DRLSDMLSFV 
661:	VQSKVSLDRV QDFLNENDTK KYDQLTIDPN GNRFAFENST ISWDKDNQDF KLKDLNIEFK 
721:	TGKLNVVIGP TGSGKTSLLM ALLGEMYLLN GKVVVPALEP RQELIVDANG TTNSIAYCSQ 
781:	AAWLLNDTVK NNILFNSPFN EARYKAVVEA CGLKRDFEIL KAGDLTEIGE KGITLSGGQK 
841:	QRVSLARALY SNARHVLLDD CLSAVDSHTA SWIYDNCITG PLMEDRTCIL VSHNIALTLR 
901:	NAELVVLLED GRVKDQGDPI DMLQKGLFGE DELVKSSILS RANSSANLAA KSSTSLSNLP 
961:	AVKEQQVSVN NNSSHFEAKK LQKSLRTEAE RTEDGKLIKE ETKEEGVVGL DVYKWYLKIF 
1021:	GGWKIVSFLA SLFLIAQLLY IGQSWWVRAW ASHNVIAKII PRAQRAIAFI SKKASHLIDW 
1081:	RGSSQISMAS AENQPSSGHS TMYYLVLYLI IGFAQALLGA GKTILNFVAG INASRKIFNM 
1141:	ILNKVLHSKI RFFDATPTGR IMNRFSKDIE AIDQELTPYI QGAFYSLIEC LSTVILITFI 
1201:	TPQFLSVAIV VSILYYFVGY FYMAGSRELK RFESISRSPI YQHFSETLVG VTTIRAFGDE 
1261:	GRFMQENLHK IDENNKPFFY LWVANRWLAF RIDMIGSLVI FGAGLFILFN INNLDSGMAG 
1321:	ISLTYAISFT EGALWLVRLY SEVEMNMNSV ERVKEYMEIE QEPYNEHKEI PPPQWPQDGK 
1381:	IEVNDLSLRY APNLPRVIKN VSFSVDAQSK IGIVGRTGAG KSTIITALFR FLEPETGHIK 
1441:	IDNIDISGVD LQRLRRSITI IPQDPTLFSG TIKTNLDPYD EFSDRQIFEA LKRVNLISEE 
1501:	QLQQGATRET SNEASSTNSE NVNKFLDLSS EISEGGSNLS QGQRQLMCLA RSLLRSPKII 
1561:	LLDEATASID YSSDAKIQET IRKEFQGSTI LTIAHRLRSV IDYDKILVMD AGEVKEYDHP 
1621:	YSLLLNKQSA FYSMCEHSGE LDILIELAKK AFVEKLNSKK D