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3.A.1.208.28
Vacuolar iron transporter, Abc3(+) of 1465 aas.  Induced by low iron and repressed by high iron.  Required for growth in a low iron medium.  Probably mobilizes stored vacuolar iron (Pouliot et al. 2010).

Accession Number:Q9P5N0
Protein Name:ATP-binding cassette transporter abc3
Length:1465
Molecular Weight:166613.00
Species:Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Fe3+

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MITANKGLSL VLLIPNLFAL VSGGLQYVFD VRRRIFRPHF SQFWTIWMKF FSIALVIITQ 
61:	IYVGYKTKNI GWNFFSVVTY CFVLFLQFAE QSTLRVPMAS LLIFWLLKVV TSLLILLFSP 
121:	YIAITSMARL LTLITLFCSL VCFISEVYVP PCNRVWYSDD TNEVEEKGIR PSEVRYANIF 
181:	SKLSFSWISS FIKFGYTNYL KESDVWLLPP DERSGNLIIG FEDWWIYHSK NKRRSLFLWK 
241:	LLFFNHWKLV ALITITKLIQ DVLAFVQPTL IQKTILFISS YTSPNPESPS RGFIIAILVL 
301:	VANFLQTLLL QQYNQLIMLL GMRWKTELLA SIYRKSLLLS SSARQNRSIG DIINYMAVDT 
361:	QKISDLPIYL FIIVSGPFQI ALALSNLYHL MGYSAFTGVA ASVILFPCNI IVANVYKKFQ 
421:	SILMKNKDSR SKLMTEIINN IRSIKLYAWE TPFLQKLLHI RNTKELSMLK KIGFITAIGD 
481:	FAWIFTTIIV TTVAFGAFII FHGKTQALTA DIVFPAVSLF NLLQFPLAML PTVISSLLEA 
541:	SVSVSRIYEF LIAQELDYNG VQRFPATEIP HEICLEIKSG TFSWSKKTLK QQVTPTLRQI 
601:	NFVAKNGELT CIFGKVGAGK SSLLEACMGN MYKNSGSVFQ CGSLAYAAQQ PWIFDATIRE 
661:	NILFGSEFDP ELYEKTIHAC CLKRDFEIFT EGDQTEVGQK GASLSGGQKS RISLARAIYS 
721:	QADIYLLDDV LSSVDQHVSR DLIKNLFGPE GFLRTHCVVL TTNSLNVLKE ADSIYILSNG 
781:	KIVEKGNYEH LFVSTNSELK QQLSEFNDEK DTQPLPEHTT SYPSTQISLA PSIHVEGLET 
841:	YSSSERKDSS NKYKSRKRNP IRQKVTEDDK GKCVAQTDEL VQRGKVKWHV YWMYFKSCSI 
901:	GLILLYFFFI ISGIMMNVAT NVWLKHWSEE NGKSSSELNP SPYFYLGIYL FFGFLSCAFI 
961:	SSSSLTMTVL CGIRSGRYLH DSMLKTILRA PMGFFETTSS GRILNRFSND VYKVDEVVSL 
1021:	TFMFFFRNSI QVLFILGVIC YSAPLSLLLI VPLFFLYLYN RAYYVRTSRE LKRLDNVTRS 
1081:	PLYAHVQESL SGLSTIRAYG MQETFVEEND LRIDTNHRVW FMFFSSSRWQ AIRVECIGDL 
1141:	IIFCTAFYGI LSAIKGSPNP GLVGFSLSYA IQITQGLSFI VQQSVDAENN TVSVERILEY 
1201:	INVKSEAPEI IPENRPPCEW PTDGAVSFNH YSAKYREDLS FALNNINIEI SPREKIGIVG 
1261:	RTGAGKSTLA MALFRIIEPT EGKIEIDNED ITKFGLYDLR SRLSIIPQES QIFEGNIREN 
1321:	LDPNHRLTDK KIWEVLEIAS LKNCISQLED GLYSRVAEGG ANFSSGQRQL ICLARVLLTS 
1381:	TRILLLDEAT ASVHAETDAI VQQTIRKRFK DRTILTVAHR INTVMDSDRI LVLDHGKVVE 
1441:	FDATKKLLEN KDSMFYSLAK ESGLI