TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.212.3
ABC-type MDR2 of 802 aas and 6 TMSs.  Exports many drugs including antifungal agents (Martins et al. 2016).

Accession Number:F2RYR3
Protein Name:ABC multidrug transporter Mdr2
Length:802
Molecular Weight:86423.00
Species:Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus) [647933]
Number of TMSs:6
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MRGSRVLQTA SFSRDAVRCS PLGLNLSSRC LATDSRAPLV HPTAFSRQYH AVSLLVLGGN 
61:	RLHRCGIFTH ASCPDVLGKL SRNAVIPQPT NLIYRQLRFA TGKSSLGENG SSQLQESTAP 
121:	VVKEVAQAEE ISQAFERSER ASQAAQINLS ARLAKDGLAS GKKSGLREIW RLITIARPEA 
181:	KVLSVAFLFL LISSSVAMSI PFSIGKILDI ATSSNPNALK DFLGISLPVF YTALGGIILL 
241:	GAAANYGRII ILRIVGERIV ARLRAKLFRN TFVQDAEFFD ANRVGDLISR LSSDTIIVGK 
301:	SITQNLSDGL RAAVSGAAGF GMMAYVSLKL SSVLALLFPP IALAAFFYGR AIRNLSRKIQ 
361:	KNVGTLTKIA EDRVVIVKTS QSFAGEILEV HRYNRQVKRI FELGKKESFI SATFFSGTSL 
421:	MGNATILALL YVGGGMVQSQ AISIGELTSF LMYTAYAGSS LFGLSSFYSE LMKGAGAASR 
481:	LFELQDRRPK ISPTAGDKVT SARGPIRFKN VAFSYPTRPA VTIFKDLDFE IPQGSNVAIV 
541:	GPSGGGKSTI ASLLLRFYSP TQGQVFINGK DVATMNAKSL RRKIGIVAQE PVLFSGSIAE 
601:	NISYGKPDAT RSQIIAAARK ANCQFISDFP DGLDTNVGPK GAQLSGGQKQ RIAIARALIK 
661:	EPDILILDEA TSALDAESET LVNSALAALL RENNTTISIA HRLSTIKRSD TIIVLDSEGK 
721:	VAEMGSYNDL NSRPDGAFTK LMAWQLSGGE GITAPVHNKP ISRGPPSETE HLQQLLQEGE 
781:	DEEYDEAETE DEPRSTDEIE KK