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3.A.3.1.5
Putative spirochete Na+, K+-ATPase, Lbi6 (1046 aas) (K. Hak & M.H. Saier)

Accession Number:B0SMV3
Protein Name:Putative sodium/potassium-transporting ATPase
Length:1046
Molecular Weight:116294.00
Species:Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) [456481]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate Na+, K+

Cross database links:

HEGENOM: HBG456486
RefSeq: YP_001840103.1   
Entrez Gene ID: 6223970   
Pfam: PF00689    PF00690    PF00122    PF00702    PF00359   
KEGG: lbi:LEPBI_I2749   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0005388 F:calcium-transporting ATPase activity
GO:0005351 F:sugar:hydrogen symporter activity
GO:0006754 P:ATP biosynthetic process
GO:0006812 P:cation transport
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis.”  Picardeau M.et.al.   18270594

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLLEYLNVDS IQILNDSKNW DDVHNSLLNK IRELEIREEI QNHFQSIPNQ TFESIGQSIL 
61:	IPHFRSKKIK SPELFLFILP QGIIVGDKHI RLVLFQMIPE NLPSLHLRLL HGLSSLLPQI 
121:	FDELMSCEKE VDVLSVVQRG EVNMKPSYKN LNHSQIAFEL QTDLQIGLTE KEAKIRLSTF 
181:	GKNVIEKEKS VPMIWKFIKS FFNLFAILLW VATGLCFVPG VDMPELGLAI FIVVLINGIF 
241:	SFFQESKSDH AVEALRKLLA NECPVIRGGN VLTVPADEIV PGDLLVLAEG DIVPADCRII 
301:	ESEDVEVDNS SLTGESTSAR RYKSENQIVL EGKFLWLEMP NILFAGSSLI KGKTKAVVFG 
361:	TGQSTEIGQI AGLTSKIKRV ESPLQKQLRQ TVISISLFAF SIGVVFLILG YWVAGLSFVQ 
421:	AFLFFIGIFV ANVPEGLLPT VTLSLALGVS RMAKRNAILK DLSSVETLGC TTVICSDKTG 
481:	TLTQNQMRVT ELFFDSKYLS PDELSNREGS QLLLECGYYC NNASLVPNPL GDPTELSLLY 
541:	LASGRIHNTS GKRVFTNGFD SIRKRMSVVV QNEDFAIVYA KGGPAEILTI CTHVYENGSV 
601:	VPLDEEKRKS LQNASDASAR QGNRILAFSY QMISNQSGPL DQMTLLNVEK DMVYLGHCCL 
661:	SDPIRPTVPD AITKCHTAGI RILMITGDHP LTAESVGRSI GIGGEKPVVI TGVQIDQMTD 
721:	VSLREWVRKG EPIFARVSPS QKLRIVTILQ ELGEIVAVTG DGVNDGPALK KADIGIAMGK 
781:	RGTEVAKEAA RMIIVDDDFA TIVSAIEEGR GVFDNIRKFS AYVLNSNPQE LIPFLLWAMI 
841:	PGFPLLMTVM GVLAVDVGTD LIPAMGLGSE PPEKGIMNRK PRNRDEKLIS LRFILNSYFK 
901:	EGMILFGACF STYFYFVYTE CGGVMPKSPE GLNMAKASPE YLQSLTAFFF PTITVQIANV 
961:	LSKRSRIESV FRMDLFANRI IWIGIGFSIL LCYLFFYTEL SSIYYFAPLP IHVYGFAFHG 
1021:	TLVLLLYSEI VKYFRRRKLD LTEIHS