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3.A.3.10.15
This protein was previously designated the functionally uncharacterized P-type ATPase 19 (FUPA19 of 1807 aas) (Thever and Saier 2009).  The unusually large size and number of TMSs is unique to this protein.  Whether this is a consequence of an artifact of sequencing is not known.  It may be a Mn2+-ATPase (by similarity).

Accession Number:I7MI73
Protein Name:E1-E2 ATPase family protein
Length:1807
Molecular Weight:207357.00
Species:Tetrahymena thermophila (strain SB210) [312017]
Number of TMSs:16
Substrate Mn2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGKQQKLFLY KKKQGLISKT QASKKSQIQQ KENIIEQNRV MDEQELKING QIKIINSQIE 
61:	GECYIQEVYA LKQQQYKQFL VILLNIITFG GYYLLENWYE RSLLKLRYCY TDDIKQATHF 
121:	LIVQLDNTFQ IVKHFEIQLQ SAISFDNRFL RYIYSEEEKY FKCIHFNYTN FLEKNQLGRK 
181:	GLNQQQLQLL EQCYGKCIMQ IPIPSYWSYL HKELINPFFM FQIFSVCIWA YDDYYAFCIA 
241:	ITLILSISTA SNICQIRSNL ASFTKIAFYE TEIMIKRDKI EKQTSSNILP GDLFYINDQM 
301:	KVPCDCILIQ GQALVNEASL TGESVPVLKY NYEFNEEVDK KCILYEGTSV IQIQNNTSEH 
361:	GCLALAIRTG FTTHRGQLVR SILFPRPHSF KFYEESIKFL KFLFALTFVA FAILLPRLYQ 
421:	TMELHYIALK LTDLLTVTVP PSLPFALQVG VVFSMQMLKQ KKIYCINSEK VVVGGRVDTV 
481:	VFDKTGTLTE DRMDLKGFLP IDDNGNFFKN ELVKEDILNV FQKENTQHIS KSMQISLNCM 
541:	GSCHSIMIRK NQQCSPKQDA LQNNYKNHLI GDPMEIQLLN ISGCKLYANG DISSSFGQQF 
601:	KIIKTLEFSS ERQKMTVICE DKSELIQENK FLYVFSKGAP EAIHKICNNY PKNYNKMLDK 
661:	YTQEGLRVLS LAYKKLPFSL ISQFQQNSSQ NTDQNNSNVN TNNLQPESIE SEMNFLGFVF 
721:	FENPLKEATA QTLQQLKEAK INIIMATGDN PQTALSVGEK CHFFDFEDNV TFINLAQLGN 
781:	NKRLTLTNSK FNTYAEVSEV DELDEYLSDE LSSFNSTDSQ ENKDQSEQPF GKDKEQLKLL 
841:	KSLKQAEELN SQGRPRDLIS KNENDERKKL SNKESSQVDD IELKDNILIQ QKSSGNKSQT 
901:	KDILNGEIKQ KCKVNEKQDQ LYICDKNSTT SSSQKIGDES IDIENDQQLN KQSNSNSSED 
961:	LKEEPDSLHL PISQYVLDSF IREALNQKSE GFVMNGAVFD EIYFKGEIND LSLMLLEKTR 
1021:	IFARMKPNHK TYLVELLQKR AVAMVGDGAN DCGALKQADI GLALSQLEAS ISAPFSGECI 
1081:	SNIIEVLIQC RAGLKTAFNN FNFIAMYSIV QFTTTTILYY CFSMQSDLQL LYIDILVVSS 
1141:	LILTMGTTNQ LSNINSMTSA SNKLSMQLPD QSLISLKNML SLGGHTLLNI ITQLVILFLL 
1201:	SKQSFFEGIE ANKQFYEKED IMTWNSSEVS TLFLFSNFIY LALSICYSDG KPFKNNFYTN 
1261:	KLFICNFMVL LAYCIQMCLV PSLNYYYFYI NTSMSFSWCS FMCIAGIGYI LLSYFYENTL 
1321:	LANSEGNSIQ NLVYYLLEAF FFVSAAPLAI MSDNVLIISA CLLVQLMFYI IVIAALQFFA 
1381:	SNIFLQSILF GRLLVMMKNW YSNKKLVLCV GLTYFLNEFF SILTVYWDQG IANQGLIIQG 
1441:	KPSIMGLSIV NEDDEGQQDQ SEANQEQKKE KHQNQQGGII QNVWGLNQSF VKKVYEDDND 
1501:	APKINFFKQL PQLKHLLFFF ISSICLKLFD WYTRNQLLGS LQPFIDQQDF SKYIFYLGMF 
1561:	GLGGIGGIVA LGIILDVRNQ EFTLRMAICS AIGLSISYIS SLLYYYGIIP QLAYEILVGA 
1621:	FEFSFYCTYQ VGVPIVLVFD LLRYGDFSYL IIPIFSALDR IVNALFNIFN KEPQNWTDSS 
1681:	TVVQPLCISL MFLSLMIQYL KDRQRSSKNF QEQLDEDDED EVQGKNTNNL LSEILEDRKG 
1741:	DGDQSNLNRS TSKNLTKNNF KIQISSDDAL SQDIHEHQFK NSLEQDTKFV IEKRNVSLKD 
1801:	NISSDFE