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3.A.3.10.18
This protein was previously designated the functionally uncharacterized P-type ATPase 22 (FUPA22 of 1212-2393 aas) (Thever and Saier 2009).  It may be a Mn2+-exporting ATPase (by similarity).

Accession Number:Q5CTJ9
Protein Name:Cation-transporting ATPase aka FUPA22a
Length:1434
Molecular Weight:164932.00
Species:Cryptosporidium parvum Iowa II [353152]
Number of TMSs:15
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mn2+

Cross database links:

RefSeq: XP_626470.1   
Entrez Gene ID: 3373632   
Pfam: PF00122   
KEGG: cpv:cgd2_2680   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0006754 P:ATP biosynthetic process

References (1)

[1] “Complete genome sequence of the apicomplexan, Cryptosporidium parvum.”  Abrahamsen M.S.et.al.   15044751

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDNIFEWLLY LQKCGFFIIS TVLLFHLMLA ICYQIRTKHV NKGKTGLFQI VGLKKSFFGE 
61:	FLRQIEIFFL IFYPFVFHVS VVAIMFYKSY TQTFESSFNW HEAVKIYARS LLTVIFCIVF 
121:	LKLLKAKYGS FEQIFLVPED LSDCEFISIS FPGSCRFSKN NIWCKLFGNY YIRVLEKFPV 
181:	TKLCRIIKRS EPINFFGTET DRYFEYRREK YWWYENEFTW SREILSRKAA ESFPVENTDF 
241:	LKVRDQVIES FGNHDKDKIL EFVGTNSLGS YPLSLWKLIF SEFTSVLNII RIMTLLDALF 
301:	YSFIVWPLCW SIITFYTISW SIIKSRRNYI ETEKVLTQHD WDIYRYLTGP YKPHSYSNAG 
361:	SSFVLSKELF PGTVIFIDKA MRIPADLLLL NGNVVVDESC LTGEATPQCK TGGIQIAPSE 
421:	FSLACDVLSN SRHLYAGSQV LEVSSTGITL AMVTRTGSAT LHGTFTSGHS NANDEHGFTE 
481:	GLPPLLTSNS RRDFTSESIS SLGRHCDLYK SIKRNWNFTP EPLWILCFIY GTFIALTDSY 
541:	TLSFEIGSIF FIVSTIIYII PFWSTSSMSL YFNNAIKYLN SEHILTTNPK KLNQLLLVDT 
601:	ICFDKTGTLT VPTFSINNVH IYPIRNNTRD HLMHLAMATC NNLIFEKAGP LQLTRKNSFS 
661:	CPSGSKLEQC LYNYSGFCGY KVFTFSSERL FIIPLCNRKT FLERVIELES HLILDYGASF 
721:	DIQQLDNVYP KNSLEYISAV CDAVEITKRY PFDETLRSQS VAIKKYSIES ELSSNLYCIR 
781:	STSMLFMKGA AEKIVELTTN YDDCSDGTSF RDWSNDILEN QVAGSYILGY CYKVVNDQAN 
841:	SSNNTLSYKH LSSSFIPLGL AQLHSPIRPE AKLVLKLLKN GNFHCPIITG DNINSAIVVA 
901:	KELGMIFNRF ASCYIDLENN LVWEIENSKR KVKFSLKNKN KIRALSGIIP QQIIQDKFQI 
961:	ALSSDAFKLF INILNLETYA GYKRKAPDEL IELSIFSKII YNTAIFARFT PELKSMAVEL 
1021:	LERLGMTVLM VGDGPNDIIA LQKANSGLLI TETIKCNGLV APFISEIFPY GLHSVCRLVI 
1081:	ESRGVVFAFV SMYQHIVLLG IFFVTCKTFL LWQSQAMIPA MAWLFIDIFC TLLPLLLFSF 
1141:	SRPKEYKIKN VNTTINHPSH DITSSHYPET CNSDCVNTRI KNLNTYAIDV NSDKYMLLVD 
1201:	NESPSALINK QIYNIKSHVG FHTFYTASFL SLLISLLGFF VISNRLVHFV LPKHGIERCF 
1261:	RYNLTIPVYL WHIRQDNIEA ASSWCYISFQ LVNQVWPIWL RSSSLIPMKT NILLIIWNIT 
1321:	MNFFILFCIW MEPSRLGCIL RINCDDQTSR SLPDNWIKLS SPFYGQYNNN IFPKFWKIEL 
1381:	TFWCVFFLML NVIISIALRT VIFKFRDFEQ IKAPNPSKTT SNRTESSLNE NVGT