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3.A.3.10.22
Manganese transporter of 1179 aas and 12 probable TMSs (Ticconi et al. 2004).  Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis. Plays an important role in pollen and root development through its impact on protein secretion and transport processes (Jakobsen et al. 2005). Functions together with LPR1 and LPR2 in a common pathway that adjusts root meristem activity to phosphate availability (Ticconi et al. 2009).

Accession Number:Q9LT02
Protein Name:Probable manganese-transporting ATPase PDR2
Length:1179
Molecular Weight:131115.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSFRVGGKV VEKVDLCRKK QLVWRLDVWP FAILYTVWLT TIVPSIDFSD ACIALGGLSA 
61:	FHILVLLFTT WSVDFKCFVQ FSKVNSIDQA DACKVTPAKF SGSKEVVPLH FRSQMTDSAS 
121:	SGDMEEIFFD FRKQRFIYSK ELGAFSKLPY PTKETFGHYL KCTGHGTEAK IATATEKWGR 
181:	NVFDYPQPTF QKLMKENCME PFFVFQVFCV GLWCLDEFWY YSVFTLFMLF MFESTMAKSR 
241:	LKTLTDLRSV RVDSQTVMVY RSGKWVKLLG TDLLPGDVVS IGRPSTQTGG EDKTVPADML 
301:	LLVGSAIVNE AILTGESTPQ WKVPIVGQRS DEKLSIKRNK NHVLFGGTKI LQHSPDKSFS 
361:	LKTPDGGCLA VVLRTGFETS QGKLMRTILF STERVTANSW ESGLFILFLV VFAVIAAGYV 
421:	LVKGLEDPTR SKYKLLLGCS LIITSVIPPE LPMELSIAVN TSLLALVRRG IFCTEPFRIP 
481:	FAGKVDLCCF DKTGTLTSDD MEFRGVGGLS NCEEAETDMS KVPVRTLEIL ASCHALVFVE 
541:	NKLVGDPLEK AALKGIDWSY KADEKALPRR GNGNSVQIMQ RYHFASHLKR MSVIVRIQEE 
601:	YLAFVKGAPE TIQERLVDVP AQYIETYKRY TRQGSRVLAL AYKRLPDMMV SEARDMDRDA 
661:	VESDLTFAGF AVFNCPIRPD SAPVLLELKN SSHDLVMITG DQALTACHVA GQVHIVSNPV 
721:	LILGRSGSGN EYKWVSPDEK EIIPYSEKEI ETLAETHDLC IGGDSIEMLQ ATSAVLRVIP 
781:	FVKVFARVAP QQKELILTTF KAVGRGTLMC GDGTNDVGAL KQAHVGVALL NNKLPLSPSD 
841:	SSKDDKSKSK KSKLPLEPAS KTITQNGEGS SKGKIPPQNR HLTAAELQRQ KLKKIMDDLN 
901:	NDEGDGRSAP LVKLGDASMA SPFTAKHASV APVTDIIRQG RSTLVTTLQM FKILGLNCLA 
961:	TAYVLSVMYL DGVKLGDVQA TISGVLTAAF FLFISHARPL QTLSAERPHP SVFSVYLFLS 
1021:	LIGQFAVHLT FLVYSVKEAE KHMPEECIEP DASFHPNLVN TVSYMVSMML QVATFAVNYM 
1081:	GHPFNQSIRE NKPFFYALIA GAGFFTVIAS DLFRDLNDSL KLVPLPQGLR DKLLIWASLM 
1141:	FIICYSWERL LRWAFPGKIS SWKHKQRAVT ANLEKKKKV