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3.A.3.2.6
Ca2+, Mn2+- ATPase (efflux)

Accession Number:Q9UUX9
Protein Name:Pmr1
Length:1025
Molecular Weight:110823.00
Species:Neurospora crassa [5141]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mn2+, Ca2+

Cross database links:

eggNOG: fuNOG04517
RefSeq: XP_964218.1   
Entrez Gene ID: 3880367   
Pfam: PF00689    PF00690    PF00122    PF00702   
KEGG: ncr:NCU03292   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0005388 F:calcium-transporting ATPase activity
GO:0006754 P:ATP biosynthetic process
GO:0006816 P:calcium ion transport

References (2)

[1] “Molecular cloning of the calcium and sodium ATPases in Neurospora crassa.”  Benito B.et.al.   10712689
[2] “The genome sequence of the filamentous fungus Neurospora crassa.”  Galagan J.E.et.al.   12712197

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MDRLSAWKDN DDVLPFYQKS PGQGTFATPE EIEQSRSGCN TPRHRITSAE SRGVADDFSY 
61:	MTPAEAATHL DTSLTHGLTP AEALSRLHDY GPNEIPHDPP EPLWLRFVKQ FQEPLILLLL 
121:	ASAGASILVG NVDDAVSISV AVTIVVSVGF IQEYRSEKSI EALNHLVPNH AHLVRKHTGA 
181:	KPVDGDDSSD IGDVAGSVTP PEDVLDAKSS KVMAAQLVPG DLVLFTTGDR IPADVRVTKA 
241:	TDLTVDASNL TGENEPVRIV AEARTRHGAT GPAADKDNST NVVYMGTLVK SGYGQGVVFA 
301:	TGGNTHFGTI ATSVSGTESP RSPLQLSMDD LGSQLSKMSF VIIGLISLVG WLQGKKLLEI 
361:	FTISISLAVA AIPEGLPIIV TVTLALGVHR MAKHNAIVRK MPKVETLGSV NVVCSDKTGT 
421:	LTTNHMTTVK MWFFGTDDAL DVDSDDEATE TKPDPAMLRI LRIGNIANNA RLAMQYTENG 
481:	AGARAVLSST QGKNAPSTYT RWVGQPTDIA MLDLLDRFKE HDVRDSIGPR VSETPFSSER 
541:	KWMGVTIGSE GGKSDKEFAY IKGSIDKVLD ACDTYLSKDG REFVMDTNRR QEAIDAAEKM 
601:	ASRGLRVLAF ASGPVTKPAK NKSPATNTVE EQYRGLTFAG LVGMSDPPRP GVSRSIRKLM 
661:	RGSVKVIMIT GDAETTAVAI GKQLGMSVTT PAVGTSGVRS VLRGDEIDAM TDEELAAAMD 
721:	HTTIFARTNP DHKLKIVKAL QSRGDIVAMT GDGVNDAPAL KKADIGIAMG KHGTDVAKEA 
781:	ADMILTDDDF STILHAIEEG KAIFNNIQNF LTFQLSTSAA GLSLVLLCTC LGYKSPLNAM 
841:	QILWINIIMD GPPAQSLGVE SVDKDVMNRP PRRRGDAVLT NPLIARVLTQ AFIIMVGTML 
901:	VYKHEMLGDG QVTRRDTTMT FTCFVLFDMF NALACRSESK SILRGEIGLF SNTLFNWAVS 
961:	LSLAGQLLVI YFPWLQEVFQ TEALGLLDLV YLVLLCSTVF FADELRKWWK YGARRHMGVN 
1021:	YSQAV