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3.A.3.23.2
Functionally uncharacterized P-type ATPase family 23 (FUPA23.2) (5 proteins from Firmicutes (778-1056aas; 10TMSs; type 2)).

Accession Number:Q835V4
Protein Name:FUPA23.2
Length:806
Molecular Weight:89248.00
Species:Enterococcus faecalis (Streptococcus faecalis) [1351]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate cations

Cross database links:

HEGENOM: HBG440326
RefSeq: NP_814991.1   
Entrez Gene ID: 1200165   
Pfam: PF00122    PF00702   
KEGG: efa:EF1268   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0006754 P:ATP biosynthetic process

References (1)

[1] “Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.”  Paulsen I.T.et.al.   12663927

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MCLRRKKEMQ ENEPIAVTAN AERYYPEDKQ GLTAAQVEER QRKGLVNAAV DTEFITTKQI 
61:	VINNVFTYFN LIFVVLGVLL MLVQSYKNMT FLPVVIINTV IGIYQEIKSK KVLDSLNILN 
121:	ATKVTVVRDG QEQEISPDEL VLDDVVLFKS GEQISGDAIV LSGEVRVNES LLTGESDEIT 
181:	KVADSQLLSG SFIVSGSCYA RIDKIGAEAY VHQLTLEAKS IKKGEQSEMV GSINRLVKWV 
241:	GIIIIPIGCV LFFQSYFINH QGLHDSIVSM EAALIGMIPE GLYLLTTVAL AASTMRLAKR 
301:	GVLLHNMKSI ESLARVDVLC VDKTGTITEN TMEVQELVPV VSIENDGTDL TNVEKLIGDF 
361:	CRTMSADNDT MKAMKEFFVT NNQREAVSYT SFSSVEKFSS VTFPEATYIL GAPEMILRDN 
421:	YEMYQSEVEH YTSQGYRLLV FGKYLGEFQE TLAAEVQPLG YILLWNPIRK EAKATFEYFA 
481:	EQNVAIKVIS GDNPLTVSNV AQAAGIIGAE NYVDARTLTT MEAQTEALEK YTVFGRVTPE 
541:	QKKQFVLLLK KLDHTVAMTG DGVNDILAMK EADCSIAMAS GNQATAQASQ VVLLDSDFST 
601:	MPEVVFEGRQ VVNNIERSSS LFLVKNIFSL LMSVFAMIFA VTYPLQPTQV TLISLFTIGI 
661:	PSTFLALEPN HRRIEGKFLF NVLSKAIPGG LTDMLVVGAL LICGDILALQ KTDISTTATL 
721:	LLVSVGFMVL YKISSPMNRY RKRVMIGCLI GMVITSISMK NLFSLTSVSP TALLLLAILF 
781:	FAADSTFQHL STISEKVQLW FYKKRH