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3.A.3.24.2
Functionally uncharacterized P-type ATPase family 24 (FUPA24) (1607aas); The first half is most like type I (Copper) ATPases, while the second half is most like type II ATPases (Ca2+).

Accession Number:B9L3W5
Protein Name:Cation-transporting P-tyep ATPase
Length:1607
Molecular Weight:169038.00
Species:Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2) [309801]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Endoplasmic reticulum-Golgi intermediate compartment membrane1 / Single-pass type I membrane protein2
Substrate copper, Ca2+

Cross database links:

RefSeq: YP_002523761.1   
Entrez Gene ID: 7357178   
Pfam: PF00689    PF00690    PF00122    PF00702   
KEGG: tro:trd_A0479   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0006754 P:ATP biosynthetic process
GO:0006812 P:cation transport

References (1)

[1] “Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum.”  Wu D.et.al.   19148287

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MNRPRIRVLH QLPGRVRLSL DPYPPDGALA QVRRLPGILA ATGNALTGTW LLRVDPALWS 
61:	TEALLEELAQ RLDQSDRAAS SGEADSERPG DTASARSRRV RVEHAVTRQV GTVSRRRLRL 
121:	AVPGLEGNPH LAQAIEDALG RLGAAVVRAS ALTGRVLVEL DESINLSEVI ASIAGLDLPE 
181:	LPPSARRVIS PFDQDLLTYG IVRSTGTALA LGLLVARQLL GRPAALTTSP VPSLIADALT 
241:	VLRGFPTLRE GMRRLLTPIG ADIATSSLGI VTQALAGQRI GLLVSFLEAL RLLTVLLPWQ 
301:	RAWQRYERQL AESSLPHPGA TARVSPGSRL PLPAVLEDGE LLTLSPAGTV EHRTRGQTVA 
361:	AGSFVLYGQA IVRYRAVEPG AAWRPRPTPL PALTQRYLDL IAPLALGAAA VNGLRAGSLA 
421:	AAGRALVLLN ARPALIGTEI ADLGAVARAL RAGTLVTRLA PGRRLVRPSV IVLDHPLLLS 
481:	DGFELDTAIS LDDALSLDEL LECSARLALE QRLPFASAFP LPTNGRRNGL RDWRRFELTG 
541:	ANGATHPVAQ KLLERGSLPV LLCERGCGRV AGVIALRPCL SAAGRELVSR CRQQGIRVLV 
601:	RGAPDTRLTW LETVGVEVLA DSDPATTIAG LRRSGQRVFY VADHLGNPSA FREADLGIGL 
661:	QPNGVVLDYP VDVLASDLAA VMTLLDIGER RDQAVRDTTL VSLASNLAAL ALGFGLPVSP 
721:	TLAAILLGGS ALLAIVLSWV RLWGQPPSSV APVYVDPEPE RWGDRAPDEL FREFATSPHG 
781:	LSASEALRRL AIEPSDSQLS PWVQAALEQL SSPLVAIMAA GAALSLAVNA PLDVLIIVGT 
841:	IAVNTLLGTW QDVRVARATS ELARLTETTA RVRRDGDEQL IPASELVPGD IVLLRFGDLV 
901:	PADARLIETN NFAVDESALT GESIPVQKDA AARDERAVVL AGSAVVSGTA VAVVVATGPR 
961:	TRLGALRRSL ELSEENRDHL TERLAQYTRL SLPISFATAA AVTLSGILRG LPPAAQLGLG 
1021:	ASLAIAAVPE GLPLLSRVAQ AATARRLARN GIVVRRLSAA EALGRVSIVC VDKTGTLTAG 
1081:	KLSVTHILTS AGLESLPGQL SELARRTLTS AALASPPPSR SDAFTHGTDA AVLRAALEAG 
1141:	LRDRLDVPRD QELPFESTQP YHAVRIGGTA YFKGSPEVLL DRCRAWLAAD GSLQPLDDAR 
1201:	HAELADHLLR LAGAGLRVLL VAEADGSVRL EDPTDLRLIG FLGLSDPLRP TVPDAVARCR 
1261:	RAGVRVVMIT GDHPATASTI ARAAGLTEDE RVITGADLAS LSDEQLAERL EQVPVIARAT 
1321:	PLDKVRIVRA LQARGHVVAM TGDGVNDSAA LRLADVGMAM GWGTEVARQA ADLILIEDDF 
1381:	AALVQALIEG RSFWRNMRRA VALLLGGNLG ELLLMGIPSL LGAPAPLNTR QVLMVNLITD 
1441:	VPPALAIALQ GPRYQRLEQL AREGETALDR PLRVDVLRRA GATAVPAALA YLWAMTASPS 
1501:	AAPAVAFTAL VAGQLAQTLE LGLSGAGLTP SLLTGTALSG AVLAATLITP PFRALLGLPA 
1561:	LTPAGWLAAG LSTVAAVAAS QAIAQLVPTE AEASSPSARP APISQPA