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3.A.3.25.3
Functionally uncharacterized P-type ATPase family 25 (FUPA25.3) (2 proteins from firmicutes; 601-623 aas; 7TMSs and an extra putative N-terminal TMS).

Accession Number:Q830Z1
Protein Name:FUPA25.3
Length:601
Molecular Weight:64083.00
Species:Enterococcus faecalis (Streptococcus faecalis) [1351]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate cations

Cross database links:

HEGENOM: HBG507745
RefSeq: NP_816262.1   
Entrez Gene ID: 1201482   
Pfam: PF00122    PF00702   
KEGG: efa:EF2623   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0046872 F:metal ion binding
GO:0046873 F:metal ion transmembrane transporter activity
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.”  Paulsen I.T.et.al.   12663927

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKHVTKLGIT IITGVLALLF EFILHQPNWA YGIILITGSV MALMMFWEMI QTLREGKYGV 
61:	DILAITAIVA TLAVGEYWAS LMILIMLTGG DSLEDYAAGK ANQELKSLLD NSPQKAHRLN 
121:	GENLEDVSVE EINVGDELVV KPGELVPVDG LVKTGTSTVD ESSLTGESKP IEKNPGDELM 
181:	SGSVNGDGSL KMVAEKTVAD SQYQTIVNLV KESAARPAHF VRLADRYAVP FTLVAYLIAG 
241:	VAWFVSKSPT RFAEVLVVAS PCPLILSAPI ALVAGMGRSS RHGVVIKSGT MVEKLASAKT 
301:	IAFDKTGTIT QGQLSVDQVQ PINAGITAAE LVGLAASVEQ ESSHILARSI VAYARKQDVP 
361:	LKNITDLAEV SGAGVKAFVD GAEIRVGKKN FVTQESQETE KIDKTTIHIS RNGTYLGRIT 
421:	FTDTVRPEAK ETMEKLHQLH LQRILMLTGD QESVAETIAA EVGITEVHGE CLPQDKLTIL 
481:	KELPKENHPV IMVGDGVNDA PSLAAADVGI AMGAHGATAA SETADVVILK DDLSKVSQAV 
541:	EIAQDTMKIA KQSVLIGIFI CVLLMLIAST GIIPALIGAM LQEVVDTVSI LSALRARRIG 
601:	Q