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3.A.3.27.3
Functionally uncharacterized ε-proteobacteria P-type ATPase

Accession Number:A6Q500
Protein Name:Heavy-metal transporting P-type ATPase
Length:801
Molecular Weight:88881.00
Species:Nitratiruptor sp. (strain SB155-2) [387092]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Endoplasmic reticulum-Golgi intermediate compartment membrane1 / Single-pass type I membrane protein2
Substrate cations

Cross database links:

eggNOG: COG2217
HEGENOM: HBG507745
RefSeq: YP_001356916.1   
Entrez Gene ID: 5360164   
Pfam: PF12156    PF00122    PF00403    PF00702   
KEGG: nis:NIS_1452   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0006825 P:copper ion transport

References (1)

[1] “Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens.”  Nakagawa S.et.al.   17615243

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSKIKCDHCH LEFDEKVMIE DEIDGKKHYF CCKGCQGVYH LLRSEGLDSF YDKLGDTKLT 
61:	PAQQKKEDLE KFDLEGFTKK YVKKRPDGLN EIYLIIEGIH CSACVWLNEK VLHKTPGIIE 
121:	ASINYTNNKA KIVWDPEEIK LSKIIETIRS IGYNAYPYDP KLQEERAVKT RRDYYARILL 
181:	AVFATMNIMW IAIAKYVGFF TGMRGDIKQI LDIAEFALAT PTLFYSGWVF FKGAYYGLKN 
241:	RFINMDFLVA TGALLTYIYS IYAMVTRSGE VYFDSVTMII TFVLVGKYLE VLSKKQAVDT 
301:	IDSLLGSVPT EVVVVQNNEK SLVPVENVEV GDTIEIKAGD KVVIDGVIIS GEGSFDESSL 
361:	TGESEPAYKK EGDEVLSGSI LLDSVIRYKA TKDFSTSLLA NIADLLEDSI AKKPKLEQLA 
421:	NQISGYFSLI ILTLALLTFA GWFWYTAEFE KSLIIAVSVI VIACPCALGL ATPMATLVGI 
481:	SEALKRGVLF KEASFLETMS KADTLVLDKT GTITKGKPSV VGVELFDPQF DQNIAYTLTE 
541:	HSNHPISKGV WEYCKAKGYE RLLPIKDIKE IKARGLEAVI EGKKIIAGSI HFLREHGIEI 
601:	AYEGENSLFA IAVNGKLMAL YELSDEIREG AAEAVAKIKE MGLEVWMLTG DNEKTAQKVA 
661:	KLVGIDQVKA KLLPQDKSAF IEKLHSEGRV VIMAGDGIND AIALACSDLA IAMGSGADIA 
721:	MSVSDVVLLD EKPMKIYESL RLSRRVFLAV KENLTLSLLY NVATIPLAML GYINPLFAAL 
781:	FMSLSSFTVV GNSMRIKFFK V