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3.A.3.3.10
Plamsa membrane proton-pumping ATPase, Pma1, of 1003 aas and 10 putative TMSs in a 2 + 2 + 6 TMS arrangement.  Leptosphaeria maculans, lacking this enzyme, displays a total loss of pathogenicity towards its host plant (Brassica napus). The mutant is unable to germinate on the host leaf surface and is thus blocked at the pre-penetration stage. Reduction in Pma1 activity may disturb the electrochemical transmembrane gradient, thus leading to conidia defective in turgor pressure generation on the leaf surface. L. maculans possesses a second plasma membrane H+-ATPase-encoding gene, termed pma2 (Remy et al. 2008).  

Accession Number:B3LDT4
Protein Name:Plasma membrane ATPase
Length:1003
Molecular Weight:110392.00
Species:Leptosphaeria maculans (Blackleg fungus) [5022]
Number of TMSs:12
Substrate H+

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAPNDDVERP RASSAAERQK SIVSMTEFEG MDEYTALQKY ILFYRDARTN PHAEKTIKKK 
61:	AWWQFWKSGS ATAAVPAADP GAVPDEFLNT ELRTGLTTTE VESRRKRYGF NEISSEKTNL 
121:	LKQFIGYFTG PILYVMELAA LLAAGLQDWI DFGVICGILL LNAIVGWYQE KQAADVVASL 
181:	KGDIAMKATV VRDNQQQTIL ARELVPGDIV VVEEGQTVPG DVRLICGYDH PEDFELYMKL 
241:	KAEDKFHDGD PEDEKDDEID EEKFDEENPI TQGHPLVACD QSSITGESLA VDKYMGEVAY 
301:	YTTGCKRGKA YGIVITTAKH SFVGRTASLV QGAQDQGHFK AIMNSIGTAL LVLVMFFILL 
361:	AWIGGFFRNI PISKAREGTD KSVTLLHYAL IMFIVGVPVG LPVVTTTTLA VGAAYLAEQK 
421:	AIVQKLTAIE SLAGVDVLCS DKTGTLTANQ LSLREPYVAE GQDVNWMMAV AALASSHNLK 
481:	SLDPIDKVTI LTIRRYPKAR EILNMGWKTE KFTPFDPVSK RITAVCHMGG DKYVCAKGAP 
541:	KAIVNLANCD EITATLYKEK AAEFARRGFR SLGVAYQKND GDWILLGLLS MFDPPREDTA 
601:	QTIVEAQQLG VPVKMLTGDA IAIAKETCKM LALGTKVYNS SKLIHGGLTG TTQHDLVERA 
661:	DGFAEVFPEH KYQVVEMLQQ RGHLTAMTGD GVNDAPSLKK SDCGIAVEGS TEAAQAAADI 
721:	VFLAPGLSTI VLAIKTARQI FQRMKAYIQY RIALCLHLEV YLVTSMIILN ETIRAELIVF 
781:	LALFADLATV AVAYDNAHSE PRPVEWQLPK IWLISVVLGL LLALGTWVIR GALFLPNGGI 
841:	IQNFGAIQPI LFLEVALTEN WLIFVTRGGK TFPSFQLIIA ILGVDALATI FTVFGWMSGE 
901:	PYQTNPPTNN TKFRDNGWVD IVTVVVIWAY SIGVTIIIAI VYYLLNRIAW LDTLGRKDRS 
961:	RKNPAIENMI AALSKLSLEH GTDKNGTTRY VLAPRAVEEE DDE