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3.A.3.32.5
Functionally uncharacterized P-type ATPase family 32 (FUPA32) (699 aas) (1 protein in Spirochetes)

Accession Number:Q73QH0
Protein Name:Heavy metal translocating P-type ATPase
Length:699
Molecular Weight:75380.00
Species:Treponema denticola [158]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Heavy metal cations

Cross database links:

HEGENOM: HBG507745
RefSeq: NP_971087.1   
Entrez Gene ID: 2740520   
Pfam: PF00122    PF00702   
BioCyc: TDEN243275:TDE_0473-MONOMER   
KEGG: tde:TDE0473   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes.”  Seshadri R.et.al.   15064399

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MNFYIAHRLP GRLRLRYSRR GLSRKQAVLV ETLVSLQEGI RSISVNPVSG SILIEYSGIS 
61:	EDEALSYIKA LNSSYLENEE LLENVEEPIV SESLTVSLGM LLAEFFIRRL LPIPVRRILA 
121:	LFSIMPRVKG GMRALKGGRP FCAETLDATA LSLSYATGDL NTAGTIAMML EMGEILEDYT 
181:	RRKSYENLTR SFLNTKETVH VLKDGNETEI SANLLQAGDT VILRIGSVIP ADGTVVSGEA 
241:	SVNQASMTGE GLPVHKVSGD TVFASTVVEE GEIHVCVKAC GRETRVSKIA DMIDRSQSLK 
301:	AASQIKSERT ADKLVFYNFL LAGLTYAFTR NFAKAASTLL VDYSCAMKLS APVCVLSAMK 
361:	NCAEHGITVK GGKFLEDFAR ADTIVFDKTG TLTESQPSVK KIITFGGRPE KAVLKIAACL 
421:	EEHFPHSLAR AVVREAENRG IKHREEHTKV SYILAHGLAS TLKGEELRIG SAHFIFDDEG 
481:	IPKTEEAEKA IEDLSKSGCS QLYLSIGKEL AGIIAIEDPV RSEAKEVVSE LHKLGIKNII 
541:	MLTGDGPQTA RSIAEKTGID RYHAQALPDT KADFIKELKA EGKKIVMIGD GINDSPALSE 
601:	ADVGIAMGQA SSIAGETADI LLPDDGLRAL PILRRIATGL IKRINVNNKA IIGINSALIA 
661:	GELAGSIPPA TAALVHNGST VAIGMSAMRS YEQPLAESI