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3.A.3.32.6
Functionally uncharacterized P-type ATPase family 32 (FUPA32) (2 proteins from Euryarchaeota)

Accession Number:A5UJX0
Protein Name:Cation transport ATPase, HAD family
Length:707
Molecular Weight:78099.00
Species:Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) [420247]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Heavy metal cations

Cross database links:

eggNOG: arNOG15807
HEGENOM: HBG507745
RefSeq: YP_001272866.1   
Entrez Gene ID: 5216647   
Pfam: PF00122    PF00702   
KEGG: msi:Msm_0293   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut.”  Samuel B.S.et.al.   17563350

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKYQVMYNNG TRIRVRSGQA AFTKKEGYGI SSLLLENNFI KKVFTSHRNG SILIYYDDVK 
61:	NRDKVFAALD KITEDDLVEV EPDMYMSSNE LTNNFWVSLS GMLVRRVLGK IVLPIPIRNL 
121:	LTVYRAIKYI WHALDSLTSF RVDVALLDGA AVTGSLLKRD FDPASSMMFL LSISDLLEDY 
181:	TLQKTKNTLK ESLTLNIDTV WVVNEDGEEI QQPISQINKD DKIKVHMGDV IPVDGKVVDG 
241:	EGMVNEATMT GEPLAVHKMP GKTVHAGTVV EEGNLIVQVY SFDKETRLNK IINLIENSEE 
301:	LKADAQSKAE ELADSIVPYS FLTTFLTYLI TRDTTKALSV LMVDFSCALK LTTPLSVISA 
361:	MKEASDNRMM VKGGKFLEKY ATADTIVFDK TGTLTNATPK VVDVISLGDY SRDEILRMSA 
421:	CIEEHFAHSI ATAIVKQAEE EGLKHDEDHS EVEYIVAHGI ATSYNGKRAV IGSRHFLFDD 
481:	EGVEISKEDE KLIDEKVCEY SVVYLAIDNK LEGIICINDP VRKEARDVIE ELKKLGIENV 
541:	IMLTGDSESG AKSSAEALGI TEYRSQVLPE DKASIVESLK EEGRTIIMVG DGINDSPALA 
601:	AADVSVSMKN SSDIAREVAD VSLLSDNLYD LITLRKLSVG MLNKIDTNYH SIIGINGSLI 
661:	ALGMFGIITP STSSLIHNLS TMLLGALSTR SVLKEPREIE VNVVETA