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3.A.3.4.3
Mg2+ ATPase (1182 aas; 18-20 TMSs) with an N-terminal (residues 1-325) transmembrane domain of 8-10 TMSs; homologous to residues 493-791 in O53781 of Mycobacterium tuberculosis (TC# 2.A.1.3.43). Residues 257-318 hit TMSs 7 and 8 in FmtC (MrpF), TC#2.A.1.3.37 with a score of 8 e-4. The last 3 TMSs of the N-terminal fused domain of 3.A.3.4.3 and 3.A.3.4.4 are homologous (e-10) to the last 3 TMSs in 2.A.1.3.43. The N-terminal domain is homologous to the 8TMS domains of 9.B.3 family members.

Accession Number:F2N2Z6
Protein Name:Mg2+ transport ATPase
Length:1182
Molecular Weight:127297.00
Species:Pseudomonas stutzeri (strain DSM 4166 / CMT.9.A) [996285]
Number of TMSs:20
Substrate Mg2+

Cross database links:

Pfam: PF00689    PF00690    PF00122    PF00702    PF03706   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015444 F:magnesium-importing ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process

References (1)

[1] “Complete Genome Sequence of the Nitrogen-fixing and Rhizosphere-associated Bacterium Pseudomonas stutzeri Strain DSM4166.”  Yu H.et.al.   21515765

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHDAFDSSAP TEHARPLIWL SWLLGAAMLG ALVVGVLQLA DASHFALVLS QAEPAWLLVA 
61:	IALQGLTYVV QGQLYRQVLT AAGTSLPLWD ATKLSLTKLF IDQALPSSGF SGAVAVVALL 
121:	QRRGIAASQV SSCFIVSVSA YFVAYLLALG AALFIAIDSG HGSLAVIATS AAFMLFCGLM 
181:	AIAAPLIAGL PQGALARRLQ HVRWMQRLLA MVFAAEPRLT RNPRLLSWAS GYSLLIVLLD 
241:	ALTLWALLHA VGHAAPFAGI FASFMLASVL RSVGIVPGGL GAFEAAAVAT LSWAGVPLAA 
301:	GLSATLLFRV LSFWLPMLPG FWLSRDTLRA GAADHHETVT PDYWSQPLDE LYASLKSGPN 
361:	GLASDAAAAR QPSVRRTYRP NLARQVGASL LRQLSSPLVL ILLIGALVAL IAHDWLDALI 
421:	VLAIVIASAL VGSLHEVRSN RAIARLREQV ASRADVWRDG RLQSLAADEV VPGDIVELSA 
481:	GSLIPADGRL VEARDCFVNQ ALLTGETFPV QKQASRIASD AALAQRDNCL FRGTSLRSGT 
541:	ARLLAVRCGL HTELGHIERS LVLRPPETEF ERGLRQFGGL LLRVMLVMVT AVLGLNLFLD 
601:	RPPLDTLMFA IALAVGLSPE LLPAILSATL SAGARRMAGR GVIVRHLNAI ENLGAMDTLC 
661:	TDKTGTLTRG VVALDGALDA DGQPSTTVLR MAWLNASLQT GLRNPLDEAI GDYARDKAPA 
721:	MTGADKLDEI PYDFVRKRLS VLLRDASEPT PRLICKGALD NVLQVSAFVQ QGDAVLPLTA 
781:	ERREALAARF AAWSAAGYRV LGLAWRSMEG ERCTVDDEQA LVFAGFLLFF DPPEPGVREE 
841:	LAALRELGVA VKIISGDNRL IARQVAESVG IDVERVITGA EIGQMRDEAL INLAPRVSLF 
901:	AEVDPNQKER IIRALQKTGH VVGFLGDGIN DAPALHAADV GISVDNAVDV AKEAADFVLL 
961:	RHELGLVRQG IDEGRRTFAN TLKYIYLTTS ANFGNMISMA VASFFLPFLP LLAKQILLNN 
1021:	FLSDIPAIGI AGDRVDADWS RTPHRWDIGE VRRFMILFGL ISSAFDLLTF GVLLYLVGEQ 
1081:	PELFRSGWFV ESLITELAII FVVRTHKPFY RSRPGRFLLV SSLLIALLTV LLPYTPVGGW 
1141:	FALQPLPATV LGAVLLITLL YAACSEWTKQ RFFARLGASR QP