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3.A.3.4.4
Mg2+ P-type ATPase (1195 aas; 18-20 TMSs) with an extra N-terminal 8-10 TMSs (residues 1-330). Similar to 3.A.3.4.3. The last 3 TMSs of the N-terminal fused domain to 3.A.3.4.3 and 3.A.3.4.4 are homologous (e-10) to the last 3 TMSs in 9.A.30.2.1. The N-terminal domain is homologous to the 8TMS domains of 9.B.3 family members.

Accession Number:C1DHA2
Protein Name:Cation-translocating P-type ATPase with extended N-terminal transmembrane region
Length:1195
Molecular Weight:127888.00
Species:Azotobacter vinelandii (strain DJ / ATCC BAA-1303) [322710]
Number of TMSs:17
Substrate Mg2+

Cross database links:

Entrez Gene ID: 7759209   
Pfam: PF00689    PF00690    PF00122    PF00702    PF03706   
KEGG: avn:Avin_02480   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015444 F:magnesium-importing ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process

References (1)

[1] “Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes.”  Setubal J.C.et.al.   19429624

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSASNDMDSS AGVFDGGARR LLWTSWLIGA AALAALVAVV LHRAEAEAFA RLIERAEPGW 
61:	FVLALALQAL TYLAQGQLYR RVARAGQVRL PLLDACRLGL MKLFVDQALP TYGVSGTLAV 
121:	TAAFQRLAVP HPVAMACLVV SLSSYLLAYV LALAVALAIV VVEGHATPLL ILAGGLFVFG 
181:	SLVAGLGVAL LAGRGLPGRL RRLAGFARVE RGLALLGQAD TRLTRNPRLL ALTVALDLGI 
241:	VLLDAGTLWA LLRSLGTEAS WSGVFAGFML ASVLRSLGIT PGGLGVFEAA AVTTLGWAGV 
301:	PLPAALSATL LFRGLSFWLP MLPGLLIARS ALRTPRARQP VAPGEPWWSW TPAQAFAALD 
361:	CAAEGLSGAA AAARTGAGET PERARPRGLA RIFLEQLRSP LVLILIFASI VSLVVHDWLD 
421:	AAIVLAIVLI GALLGAGQEY RASSALERLR RRVAITARVH RDGAPVEIPA GEVVPGDVIE 
481:	LSAGSLIPAD GLVLAARDCF VGQGLLTGET FPVEKRPGLA EPGASLAERD NCLFMGSSLR 
541:	SGTATLLAVR TGADSEYGRI ARSLSLRPPE TEFERGLRHF GALLLKVMLL MVVGVLAANI 
601:	LLERPTVETL MFAIALAVGL SPELLPAILG ITLARGAQRM ARRGVIVRRP NAIENLGAMD 
661:	VLCTDKTGTL TRGVVQLDGA LDPDGQPSER CLLLAGLNAS LQTGLANALD AALVAGVRER 
721:	GLDLGAFGKL DEIPYDFVRK RLAVVVEGAD GEALMIVKGA LDKVLERCTR IGEAEAAPLD 
781:	EAALAALRER YAQWSAQGYR VLGLASRPVP RQARYTESDE NELAFVGFLL FFDPPEPGVR 
841:	DTLRDLDRLG VAVKIISGDN RLVTRHVAEA VGIPAGRVIT GGEMLRMRDE ELLNLAPQVA 
901:	LFAEVDPNQK ERIILALQKT GHVVGFLGDG INDAPALHAA DVGVSVEQAV DVAKEAADFV 
961:	LLRHDLDLLR QGIDEGRHTF ANTLKYIFIT TSANFGNMIS MALASLFLPF LPLLAKQILL 
1021:	NNFLSDIPAM GIAGDNVDRE WERTPHHWNL REVRNFMVVF GLVSSAFDLL TFGTLFYFVG 
1081:	ERPELFRTGW FVESLLTELA IVFVVRTYKP FYRSRPGRLL LSSTLAVMLL TLLLPYTPAG 
1141:	AWFDLVPLPP ALLAMIGLIT LLYAATSEAV KRRFYAAARM PRGAARRYRG VEPGR