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3.A.3.5.11
Chloroplast envelope Cu+-uptake ATPase, PAA1 or HMA1.  Essential for growth under adverse light conditions (Seigneurin-Berny et al. 2006).

Accession Number:Q9SZC9
Protein Name:Paa1
Length:949
Molecular Weight:99997.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cu+

Cross database links:

Genevestigator: Q9SZC9
eggNOG: KOG0207
HEGENOM: HBG507745
RefSeq: NP_974675.1   
Entrez Gene ID: 829490   
Pfam: PF00122    PF00403    PF00702   
BioCyc: MetaCyc:MONOMER-14495   

Gene Ontology

GO:0009941 C:chloroplast envelope
GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0006825 P:copper ion transport
GO:0009767 P:photosynthetic electron transport chain

References (2)

[1] “Cloning of a cDNA encoding a putative metal-transporting P-type ATPase from Arabidopsis thaliana.”  Tabata K.et.al.   9188794
[2] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.”  Mayer K.F.X.et.al.   10617198

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MESTLSAFST VKATAMARSS GGPSLPLLTI SKALNRHFTG ARHLHPLLLA RCSPSVRRLG 
61:	GFHGSRFTSS NSALRSLGAA VLPVIRHRLE CLSSSSPSFR SISSGGGSGF GGYNGGSGGG 
121:	GGGGSESGDS KSKLGANASD GVSVPSSDII ILDVGGMTCG GCSASVKKIL ESQPQVASAS 
181:	VNLTTETAIV WPVPEAKSVP DWQKSLGETL ANHLTNCGFQ STPRDLVTEN FFKVFETKTK 
241:	DKQARLKESG RELAVSWALC AVCLVGHLTH FLGVNAPWIH AIHSTGFHVS LCLITLLGPG 
301:	RKLVLDGIKS LLKGSPNMNT LVGLGALSSF SVSSLAAMIP KLGWKTFFEE PVMLIAFVLL 
361:	GRNLEQRAKI KATSDMTGLL SVLPSKARLL LDGDLQNSTV EVPCNSLSVG DLVVILPGDR 
421:	VPADGVVKSG RSTIDESSFT GEPLPVTKES GSQVAAGSIN LNGTLTVEVH RSGGETAVGD 
481:	IIRLVEEAQS REAPVQQLVD KVAGRFTYGV MALSAATFTF WNLFGAHVLP SALHNGSPMS 
541:	LALQLSCSVL VVACPCALGL ATPTAMLVGT SLGARRGLLL RGGDILEKFS LVDTVVFDKT 
601:	GTLTKGHPVV TEVIIPENPR HNLNDTWSEV EVLMLAAAVE SNTTHPVGKA IVKAARARNC 
661:	QTMKAEDGTF TEEPGSGAVA IVNNKRVTVG TLEWVKRHGA TGNSLLALEE HEINNQSVVY 
721:	IGVDNTLAAV IRFEDKVRED AAQVVENLTR QGIDVYMLSG DKRNAANYVA SVVGINHERV 
781:	IAGVKPAEKK NFINELQKNK KIVAMVGDGI NDAAALASSN VGVAMGGGAG AASEVSPVVL 
841:	MGNRLTQLLD AMELSRQTMK TVKQNLWWAF GYNIVGIPIA AGVLLPLTGT MLTPSMAGAL 
901:	MGVSSLGVMT NSLLLRYRFF SNRNDKNVKP EPKEGTKQPH ENTRWKQSS