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3.A.3.5.20
The gold (Au2+) resistance ATPase, GolT (regulated by GolS in response to Au2+; it may function with a cytoplasmic metal binding protein, GolB (AAL19308; Pontel et al., 2007).

Accession Number:Q8ZRG7
Protein Name:GolT
Length:762
Molecular Weight:80181.00
Species:Salmonella typhimurium [90371]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Au2+

Cross database links:

HEGENOM: HBG507745
RefSeq: NP_459348.1   
Entrez Gene ID: 1251872   
Pfam: PF00122    PF00403    PF00702   
BioCyc: STYP99287:STM0353-MONOMER   
KEGG: stm:STM0353   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSQSENRHDT ISLLIEGMTC ASCVARVEKG IKAVPGVTDA TVNLATERAT VRGTASAEAV 
61:	IAAIEKTGYK ARPIETAGQG EDDSEEKKEA ERVRLKRDLI LASVLALPVF VLEMGSHLIP 
121:	GMHEWVIKTI GLQQSWYWQF ALTLLVLTIP GRRFYLKGFP ALARLAPDMN SLVAVGTAAA 
181:	FGYSLVATFT PDLLPEGTVN VYYEAAAVIV ALILLGRFLE ARAKGRTSEA IKRLVGLQAR 
241:	VAHVLREGRI VDIPVDEVVL GDCVEVRPGE RIPVDGEVTE GRSFVDESMI TGEPIPVEKS 
301:	AGSAVVGGTV NQKGALTLRA TAVGGQTMLA QIIRLVEQAQ GSKLPIQAVV DKVTLWFVPM 
361:	VMLIAALTFV VWLAFGPSPA LTFALINGVA VLIIACPCAM GLATPTSIMV GTGRGAEMGV 
421:	LFRKGEALQL LKDAKVVAVD KTGTLTEGRP VLTDLDVASG FERREVLAKV AAVESRSEHP 
481:	IARAIVVSAE EEGIALPGMS GFESVTGMGV YATVDGTRVD VGADRYMREI GVDISGFATT 
541:	AERLGQEGKS PLYAAIDGQL AAIIAVADPI KPSTPAAINA LHQLGIKVAM ITGDNARTAQ 
601:	AIARQLGIDD VVAEVLPEGK VEAIRRLKAA YGQVAFVGDG INDAPALAES DVGLAIGTGT 
661:	DVAVESADVV LMSGNLQGVP NAIALSKATI RNIHQNLFWA FAYNTALIPV AAGALFPVWG 
721:	ILLSPVFAAG AMAMSSVFVL GNALRLRRFR APMATPSDTS TT