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3.A.3.5.25
The putative copper ATPase, Pae1

Accession Number:Q8ZUJ0
Protein Name:Cation-transporting ATPase (P-type)
Length:789
Molecular Weight:85135.00
Species:Pyrobaculum aerophilum [13773]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate Cu+

Cross database links:

HEGENOM: HBG507745
RefSeq: NP_560235.1   
Entrez Gene ID: 1463578   
Pfam: PF00122    PF00403    PF00702   
BioCyc: PAER178306:PAE2758-MONOMER   
KEGG: pai:PAE2758   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.”  Fitz-Gibbon S.T.et.al.   11792869

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MEISVGLKVK GRETVLKILG MHCATCSLTV QKALLSVPGV KWAEASLASN EAKLVVDPEA 
61:	LDYSELLKAV RRVGYDVFRE SAYIAAEFRP EEAEAAERRV RGWGVFYAKA NPATGVIYVE 
121:	YNPLELDADM VAKRLEEAGY KVREVKKGDV EVDVDRRVAE LEARDIRRRL IPAVLISTVL 
181:	APTMLGIKVV PPLAQMALTA IVQFYSGWRF ISGAARAFRN KTANMDTLVT LGTLSAFLYS 
241:	SYAVFSGEPT FFEVSAVIIT FILAGRYIEI LMKLRTGDAV RKLAQLQPPK ARVKRGDEWV 
301:	EVNASEVKPG EVVEVREGER IPVDGYVDEG AGAVDESAFT GEPLPVEKKA GDLVLAGTVL 
361:	IKGRLLIRAT RTGGATYLAE VVKLVRQAQN ARLPIQRLVD RVSGVFTWAV MGVATATFAA 
421:	WIALGAPVWQ ALMFAVAVLV VACPCALGLA TPLAIVVGVG RAAEKGLLIK NPEAIEKALR 
481:	AKFVAFDKTG TLTAGAPKVV KYVGDEHALA LAASAEAKSS HPIGVAVVEF AIKRGAKLAE 
541:	PEAYDTFPGM GVYAKVNGAV VGIGNEKLVE GMGAEIPGEI RREAERYRAE GYTVAYIVVD 
601:	GRVRGFVVVG DEIRQEARDV VERLKRWGYQ PVIISGDHEV AVAKVAERLG IGKYYGGKTP 
661:	DEKAEIVKEL RKEGGVIFIG DGINDAPALA SADMGIAVAT GTEVAKEAGD VVVRRGDLSK 
721:	VAEFIDISRK IMKNAKFNLF WAFVYNTALI PISAGLFYPA LYLRPELAGL AMALSSISVT 
781:	LNSLRLRRA