TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.3.5.29
The copper (Cu2+) transporting ATPase, Ccc2

Accession Number:O59666
Protein Name:Copper-transporting ATPase ccc2
Length:904
Molecular Weight:97895.00
Species:Schizosaccharomyces pombe (Fission yeast) [4896]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Golgi apparatus1 / Multi-pass membrane protein2
Substrate Cu2+

Cross database links:

eggNOG: fuNOG05708
HEGENOM: HBG507745
Entrez Gene ID: 2540525   
Pfam: PF00122    PF00403    PF00702   
KEGG: spo:SPBC29A3.01   

Gene Ontology

GO:0000329 C:fungal-type vacuole membrane
GO:0005794 C:Golgi apparatus
GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0006878 P:cellular copper ion homeostasis

References (2)

[1] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[2] “ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.”  Matsuyama A.et.al.   16823372

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MYTTTLSVQG MTCTSCVASI QSMLEGVEGI EQFTISLLLE RAIAVHDPSI ISPDQIAEKI 
61:	EDCGFDASVI SSTEGEHGVM ANYLLLSPMQ AEQWTKVHNH INELQGVLSV NCSSSPDAAI 
121:	RVIYDSEITG PRSIMKEILS MGVKCTFQPV DSSTSRILSL QRGSQIRVWK IRFIISISFS 
181:	LAVMFLPQIF DSCDSMRAAF LVPHYFGICA GHIISLVLSL PVQFGVGRVY YSAAYHALKR 
241:	GTANMDVLVS LGSTVAFAAS IFFMILYSAR HADNPAPIFF DTADMLLTFV TLGRYLESKA 
301:	KGSTSAALSQ LLSLAPSSAT IIEDNEQIEI LADLIERGDL ILVKPGEIIP VDGTVVEGSS 
361:	YVDESSVSGE PVPVHKTIDD ELLSGTANGN GRLLVKATKS PRESQLAVIV DLVQRAQISH 
421:	APIQQFADRV AGIFVPVIVA LSISTFTFWF LFTKYSSKYP SVFDDPMGKF AVCLKLTISV 
481:	VVVACPCALG LSTPTAVMVG TGVGALNGII IKGGEILERL NQVDTVVFDK TGTLTVGKLS 
541:	VTDISIVDNL EELLDIPKNI FWAFVKASES SSEHPIGKAI TEKASEFTDV SEIGIESFNA 
601:	VPGEGVDVVL RWKERTFHAL LGNSLLLEHN NVSIPDDFDS KLKLSSSSGL TCVRIAIDGQ 
661:	FVGFLGCMDQ VRPDSYQTVS ALKQLGKKVC LLTGDQKATA RRVAQGLEID FSDVYAEAVP 
721:	SQKAEIIQKL KDQKHCVAMV GDGINDSPSL VLADVGIAPI NGSGIALESA DVILVRKGVL 
781:	LDTAVSFDLS RVIVKRIKMN LVWACIYNFV MIPIAMGFFL PWGIYLNPMW ASAAMMFSSL 
841:	SVLASSLLLR RWKKPKSLIF SEADDVETES STNSSVLQKV YTATRSIFGR NKSSNKYQPV 
901:	ANEV