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3.A.3.5.4
Ag+-ATPase (efflux)

Accession Number:Q9ZHC7
Protein Name:SilP
Length:824
Molecular Weight:88221.00
Species:Salmonella typhimurium [90371]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Ag+

Cross database links:

Pfam: PF00122    PF00702    PF04945   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0006825 P:copper ion transport

References (1)

[1] “Molecular basis for resistance to silver cations in Salmonella.”  Gupta A.et.al.   9930866

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLQICIRRVT VKNDNAVEHN NQDCFLSRTS SRDESHALHK VRESVCGMVI LPDKAHSSIR 
61:	YQDHQLYFCS ASCESKFKAH PDHYFTEDAS EHHHHHDHHE VSPDKIKQSH RQAEKEISEG 
121:	VWTCPMHPEI RRSGPGSCPV CGMALEPLVA TASTGTSDEL RDMTRRFWLG LLLAFPVLIL 
181:	EMGSHLFPAL RNTVPPQYNT WLQLLLASPV VLWCGWPFFA RAGMSLRNRS LNMFTLVAMG 
241:	TGVAWVYSVI ATVFPSWFPA SFRNMDGLVA IYFEAAAVIT VLVLLGQVLE LRAREQTSGA 
301:	ITALLNLAPK TARRLDQDGH ETDINAEDVL PGDKLRIRPG ESIPVDGIVV EGKTTVDESM 
361:	VTGESMPVTK TEGEPVIGGT INQTGSLIIR AEKVGDETML SRIVQMVADA QRSRAPIQRM 
421:	ADSVSGWFVP LVILIAVVAF MIWSVWGPEP RMAHGLIAAV SVLIIACPCA LGLATPMSIM 
481:	VGVGKGAQAG VLIKNAEALE RLEKVDTLVV DKTGTLTEGS PTVTGIISLN PGGETSLLRV 
541:	TAAVDKGSQH PLGMAVVKAA QEKGIAIPAV THFNAPSGKG VSGDVEGQRV VIGNELAMQE 
601:	NSIVIDNQKA VADTLRMEGT TVIYVATDGH LAGLIAISDP VKATTPDALK ALRQAGIRIV 
661:	MLTGDNQLTA EAVARKLGID EVEAGILPDG KKAVITRLKA SGHVVAMAGD GVNDAPALAA 
721:	ADVGIAMGTG TDVAIESAGV TLLKGDLMIL NRARHLSEIT MKNIRQNLFF AFIYNALGVP 
781:	VAAGLLYPVY GILLSPVIAA AAMALSSVSV IVNALRLKSV RLGK