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3.A.3.5.8
Cu+ transporting ATPase (intracellular, in the trans-Golgi membrane), Ccc2

Accession Number:Q5AG51
Protein Name:Copper-transporting P-type ATPase
Length:1204
Molecular Weight:131383.00
Species: [5476]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Cu+

Cross database links:

RefSeq: XP_720634.1    XP_720761.1   
Entrez Gene ID: 3637579    3637821   
Pfam: PF00122    PF00403    PF00702   
KEGG: cal:CaO19.11803    cal:CaO19.4328   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (2)

[1] “The diploid genome sequence of Candida albicans.”  Jones T.et.al.   15123810
[2] “Deletion of the copper transporter CaCCC2 reveals two distinct pathways for iron acquisition in Candida albicans.”  Weissman Z.et.al.   12067343

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKSSAILESN PNQNNNVTVV LEVLDLHTAK DITDVINILD ELFPKLKSKD FDHQELTLIY 
61:	DSNDYDDMSI LNAISEIGFP VKILSSTAPQ CKTTVNIQGM TCGACSASIT EALEKTPGVY 
121:	KASISLVTEN GLIMHSPKLS PENIITIIED CGFDAQIESS KTKQSSAPES SQDQSKRLNT 
181:	TIGIIGMTCG ACSASITNVL EKLPGVENVS VSLITEEASI VHDSTITTVQ QLKEAIEDCG 
241:	FTPTFNKSIN LNQYQNTNDS NEEVTLKIVG VNHTTDLIGL RYNIEAYLRS ISGVQKFELT 
301:	LRGMNASSNI MPTQVGTLIT EEDTIADVKS LVNELVFQYD SDSVGIRDII DGLNTISDNI 
361:	EFMVINSLDQ SSATQLKLLS KVKDINYWKK IFIQSLLFGI PVLFLNHTKN WPIWKTTMIF 
421:	PGLYLVSLLE LILSTYIQFY LGSVFIKKFS SFLRKKFKGA TMDVLVCIST MCSYIFSLTT 
481:	IIVSVWNGQK NGPPPVLFDT LVMLISFVSF GKLLENKAKG ATSTALSSLL SLTPSTCTII 
541:	NDIPGYQKFI EDQQSLEKSE KSNSLSMQEF PTRVISIDLV QPNDIAIVLP GGKVPADGEI 
601:	VFGETEIDES LITGEPLPVY KKLKDKVIGG SINGPHLIHI KVTHTGKKSQ LQQIINLVKE 
661:	SQVNKAPVQK FSDYIAARFV PFVLLLAIFT FILWMIICFT IHQDKLPKIF QNETNGKFFV 
721:	CLKLSISVIV VACPCALGLA APTAVMVGTG VGAINGVLIK GAKVLEKITG VNIILFDKTG 
781:	TLTTGEMSLV NFQPIMSKSS ITISDWWKLV GSVECHSEHP IGRALTKSAK TNLNLNFDDD 
841:	HFDTTVNDIN VLIGLGIQAN VTLANNPQTQ FNVYVGNDKL IESKFPNLLN NIDEKLLHSA 
901:	NTVSHVIIDG EYSGYIELTD ALKSGSWEVV NYLKTQGYIV GMVTGDNRGA ALKIAQEVGI 
961:	PFDNVFYEVS PIHKDNVITD LHNRLGGNQS SSVNVAFIGD GINDAPALAK ADIGMAISSG 
1021:	TDIAIESADI VLIGGRSNQT DLHGVVNALQ ISTATFNRIK INFLWAIIYN IFMLPFAMGC 
1081:	FLPLNIVLPP VAAGAAMMFS SLSVVFSSLL LKRWTPPKIE TKKTFIDDLE MGNNATGGDG 
1141:	DGFSLKNGTI EEFNNVKRKS AVNFSSLFAK MTTTRRNRRG GGGGGGRSNG NNNQSYELVS 
1201:	NRFS