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3.A.3.5.9
Cu+ transporting (copper detoxification) ATPase, Crp1

Accession Number:Q9UVL6
Protein Name:Crp1
Length:1197
Molecular Weight:131595.00
Species:Candida albicans (Yeast) [5476]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Cu+

Cross database links:

Pfam: PF00122    PF00403    PF00702   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “The high copper tolerance of Candida albicans is mediated by a P-type ATPase.”  Weissman Z.et.al.   10737803

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MQKFIINFAN IHCDKCEGII RNVVSRYYKI SDETDLNANI KPSEVIFKLE NNEVTLYGND 
61:	LIDFHGDIKS IIKSLGKSGF DILSWDLHNG DETVSSSQIV NTNIQGANEP DGFIDIVGMY 
121:	HKFINSRNKK KHMKYCKVCQ ESQQHKKKST DSDFSSSSED TVVEIPHQEF RASFLVTGMT 
181:	CASCAQSITD NLRSILGESK NEDEPNFSVN VIQQSVVVII PNKQIINKIV DAINDMGFDC 
241:	KLIEVLPVQR SVNTKVTALI GGMTCAACAN SIDSAVKELP FILESGINVV TKAAQFVLED 
301:	DGGSNIAKLK ETIEDCGFDF ELLSTEKVNY TSGKQKPRSI NLKVNGMFCN HCPDIITQYL 
361:	TNYGDAVVIN DPISLDHPVI KFTYVPSQTL KTRKILFDLN HLKDDGNGGY TITPDEKGAF 
421:	ECEIIKPVTV DEHVRKLAHR EVLGLAIRLA IATLFAIPTF IFGIVAMSLL PKHHPFRIWV 
481:	EDPLWVGNVS RNSWILFILA TPVYFFAADT FHRKAIKEIK SLWFHKNSFK SRLLKFGSMN 
541:	LLMSLGTTVA YFASIVLIGL SATQKPMTHH GLHTTYFDSV VFLSFFLLIG KLLQSYSKSK 
601:	TADAISELSK LKQTEATLIE DNKDTRVDIQ LLEIGDQIRI GTGESPPVDC VLVEGSTEFD 
661:	ESALTGESTP VKHQEGHQIF SGTVNIGNSS VVGKVTSLEG DSLLNQIVNT VRDGQMRKAP 
721:	MERTADLITG YFVPLIIACA VITWVIWLAL GYSGALPQSY LDIDVGGWTV WSLEFAIAVF 
781:	VVACPCGIGL AAPTALFVGS GLAAKNGILA KGGGVAFQDG ANVNIVCFDK TGTLTKGELT 
841:	ITDFHFPDKS SIAKTFALQV ARDLEVPSHH PLGKAVKSFV TSYDGKSLTA NKIPQVETVP 
901:	GKGLRGQIIY DEGDDIWNEY KPTQAILGNE KLMEENDIEF TEKERQCLKK WKGECKSVIL 
961:	VGLQCESYFK DSKFHLALIM AARDQLRPET KKVIEFLKHK DIECWMITGD NKLTADAIAK 
1021:	EIGIENVVSE VLPDEKEAQI KKIRQLNSGG KKEPVIAMIG DGINDAPALA SADVGIALSS 
1081:	GADLAVTSSD FILLNKMHPL VSLATLLDIC SKVFQRVKLN FGWSLVYNLI ALPIAAGVIY 
1141:	PYKNSRLDPV WASAAMALSS VSVVLSSLAL KLYKPSLKAE DFGVDDSTES ELSPNEV