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3.A.3.6.11
The Zn2+ efflux P-type ATPase, CadA1 (Leedjarv et al., 2007)

Accession Number:Q88RT8
Protein Name:CadA-1 aka Cadmium translocating P-type ATPase
Length:665
Molecular Weight:70581.00
Species:Pseudomonas putida (strain KT2440) [160488]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

eggNOG: COG2217
HEGENOM: HBG507745
RefSeq: NP_742211.1   
Entrez Gene ID: 1043522   
Pfam: PF00122    PF00702   
KEGG: ppu:PP_0041   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0046872 F:metal ion binding
GO:0046873 F:metal ion transmembrane transporter activity
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440.”  Nelson K.E.et.al.   12534463

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKSLLERPDD QAGHEGHSHE HGGIFGMNTE LIFALICGAL LGAGALAGKL GLIDRLPLIL 
61:	YVSAYVFGGW FTTKEAVTNI RQKRFEIDSL MLLAAVGAAS IGAWAEGALL LFLFSLGHSL 
121:	ESYAMGRAKK AIEALSKLAP ATAIVRRANG TVEMPVELLV PGDVVIVRPN DRLPADGFVV 
181:	VGSSSINQAP VTGESVPVDK QPVPDAELAR SKPDAVDAAS KVFAGTINGE TLIEVEVTRR 
241:	STESTLARVI KMVSEAEVRK SPTQRFTDRF QRIFVPLVLL LVVGLLFAGI FLDEPFRDSF 
301:	YRAMAVLVAA SPCALAIATP SAILSGIARA ARGGVLIKGG APLEELGSLN AMAFDKTGTL 
361:	TEGRPRITDV IPIGGTQIED LLNVAIAVES MSDHPLAAAI VRDGEEMIGT RRRFQAKNMS 
421:	NMIGRGVRAE LDGQFVWIGK VEMFGTNGIP ALSKAALEAA ERLRQSGRTT MVVRRADKDL 
481:	GAIGLLDTPR EGAKEALQKL REMGIERMVM ISGDHNRVAE AVAKQVGLDE AWGDLMPEDK 
541:	VKAIKNLRLS AKVAMVGDGV NDAPAMASSS VGIAMGAAGS DVALETADIA LMADDIRQLP 
601:	FAVGLSRHTR SIIHQNLFVS LGIVAILVPS TIMGLSIGAA VAIHEGSTLL VVFNALRLLA 
661:	YRRST