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3.A.3.6.14
The heavy metal (Zn2+, Cd2+) P-type ATPase, Smc04128 (Rossbach et al., 2008)

Accession Number:Q92T56
Protein Name:Smc04128
Length:743
Molecular Weight:76187.00
Species:Rhizobium meliloti (Sinorhizobium meliloti) [382]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Zn2+, Cd2+

Cross database links:

HEGENOM: HBG507745
RefSeq: NP_384230.1   
Entrez Gene ID: 1231755   
Pfam: PF00122    PF00403    PF00702   
BioCyc: SMEL266834:SMC04128-MONOMER   
KEGG: sme:SMc04128   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0005261 F:cation channel activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021.”  Capela D.et.al.   11481430

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTGIFRETRF RVDGMDCASC AAKIDTAVRR VAGVEDVNVS VAAGTMTVRH AARDDIGAQV 
61:	MRKVGVLGYG LSPLDVAAER QPAQSEHACC GHDHAAGSAH GEASHDHGHS TALPASTKPS 
121:	SRFTAPLPWW RTAKGKLTLA CGVALASAYA IGQFVPATEP WIFTLAMLVG LLPIARRALM 
181:	AALSGTLFSI EMLMTIAAAG AVFIGAGEEA AMVVFLFLIG ELLEGVAAGK ARASIQALTA 
241:	LVPKSALLEE NGRTVEVPAE SLAPGAIVLV RPGDRLPADG IIVSGESSVD EAPVTGESTP 
301:	VLKEAGANVF AGTVNGDGAL RVRVTAAAAD NTIARVIRLV EEAQEKKAPT ERFIDRFSRY 
361:	YTPGVVLVAA LVAVIPPLFF GGLWQDWIYK GLALLLIGCP CALVISTPAA IAASLSAGAR 
421:	RGLLIKGGAV LENLGRITAV AFDKTGTLTE GRPKLTDIVG FGRSEAEILG YAAALEQGSS 
481:	HPLAHAVLSR AEADGLALLP VEGARAIGGK GVAASADGVE LFLGSPEAAR ERAPLAAEDL 
541:	ARIETLQGEG KTVSVLVVGG RAAGALAMRD EPRADAAAGL RALADQGLRV VMLTGDNRAT 
601:	AEAIAGRLGG IEAHAGLLPE DKQRIVSRLR AEGLVVAKVG DGINDAPALA AADVGIAVGG 
661:	GTDVALETAD AASLHARVSD VAAMVKLSRV TMRNIHQNIA IALGLKAVFL ATTIAGVTGL 
721:	WPAILADTGA TVLVTINALR LLR