TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.3.8.6
Golgi phospholipid transporting (flipping) ATPase3 (1213aas; 10TMSs). Involved in growth of roots and shoots. Uses a β-ATPase3 subunit, ALIS1 (TC#8.A.27.4) (Paulsen et al., 2008).

Accession Number:Q9XIE6
Protein Name:Putative phospholipid-transporting ATPase 3 - Arabidopsis thaliana (Mouse-ear cress).
Length:1213
Molecular Weight:137753.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate phospholipids

Cross database links:

Genevestigator: Q9XIE6
eggNOG: KOG0206
HEGENOM: HBG745019
RefSeq: NP_176191.1   
Entrez Gene ID: 842275   
Pfam: PF00122   
KEGG: ath:AT1G59820   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0000287 F:magnesium ion binding
GO:0004012 F:phospholipid-translocating ATPase activity
GO:0006754 P:ATP biosynthetic process
GO:0048194 P:Golgi vesicle budding
GO:0015914 P:phospholipid transport
GO:0048364 P:root development
GO:0048367 P:shoot development

References (3)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “The Arabidopsis P4-ATPase ALA3 localizes to the golgi and requires a beta-subunit to function in lipid translocation and secretory vesicle formation.”  Poulsen L.R.et.al.   18344284

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MVRSGSFSVD SSATHQRTPS RTVTLGHIQP QAPTYRTVYC NDRESNQPVR FKGNSISTTK 
61:	YNVFTFLPKG LFEQFRRIAN IYFLGISCLS MTPISPVSPI TNVAPLSMVL LVSLIKEAFE 
121:	DWKRFQNDMS INNSTVEILQ DQQWVSIPWR KLQVGDIVKI KKDGFFPADI LFMSSTNSDG 
181:	ICYVETANLD GETNLKIRKA LERTWDYLVP EKAYEFKGEI QCEQPNNSLY TFTGNLVVQK 
241:	QTLPLSPDQL LLRGCSLRNT EYIVGAVVFT GHETKVMMNA MNAPSKRSTL EKKLDKLIIT 
301:	IFCVLVTMCL IGAIGCSIVT DREDKYLGLH NSDWEYRNGL MIGFFTFFTL VTLFSSIIPI 
361:	SLYVSIEMIK FIQSTQFINR DLNMYHAETN TPASARTSNL NEELGQVEYI FSDKTGTLTR 
421:	NLMEFFKCSI GGVSYGCGVT EIEKGIAQRH GLKVQEEQRS TGAIREKGFN FDDPRLMRGA 
481:	WRNEPNPDLC KELFRCLAIC HTVLPEGDES PEKIVYQAAS PDEAALVTAA KNFGFFFYRR 
541:	TPTMVYVRES HVEKMGKIQD VAYEILNVLE FNSTRKRQSV VCRFPDGRLV LYCKGADNVI 
601:	FERLANGMDD VRKVTREHLE HFGSSGLRTL CLAYKDLNPE TYDSWNEKFI QAKSALRDRE 
661:	KKLDEVAELI EKDLILIGST AIEDKLQEGV PTCIETLSRA GIKIWVLTGD KMETAINIAY 
721:	ACNLINNEMK QFVISSETDA IREAEERGDQ VEIARVIKEE VKRELKKSLE EAQHSLHTVA 
781:	GPKLSLVIDG KCLMYALDPS LRVMLLSLSL NCTSVVCCRV SPLQKAQVTS LVRKGAQKIT 
841:	LSIGDGANDV SMIQAAHVGI GISGMEGMQA VMASDFAIAQ FRFLTDLLLV HGRWSYLRIC 
901:	KVVMYFFYKN LTFTLTQFWF TFRTGFSGQR FYDDWFQSLF NVVFTALPVI VLGLFEKDVS 
961:	ASLSKRYPEL YREGIRNSFF KWRVVAVWAT SAVYQSLVCY LFVTTSSFGA VNSSGKVFGL 
1021:	WDVSTMVFTC LVIAVNVRIL LMSNSITRWH YITVGGSILA WLVFAFVYCG IMTPHDRNEN 
1081:	VYFVIYVLMS TFYFYFTLLL VPIVSLLGDF IFQGVERWFF PYDYQIVQEI HRHESDASKA 
1141:	DQLEVENELT PQEARSYAIS QLPRELSKHT GFAFDSPGYE SFFASQLGIY APQKAWDVAR 
1201:	RASMRSRPKV PKK