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3.A.3.9.3
Monovalent alkali cation (Na+ and K+) ATPase (efflux of both cations)

Accession Number:O13398
Protein Name:ENA2
Length:1082
Molecular Weight:119901.00
Species:Debaryomyces occidentalis (Yeast) (Schwanniomyces occidentalis) [27300]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, K+

Cross database links:

Pfam: PF00689    PF00690    PF00122    PF00702   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0015662 F:ATPase activity, coupled to transmembrane m...
GO:0006754 P:ATP biosynthetic process
GO:0006812 P:cation transport

References (1)

[1] “P-type ATPases mediate sodium and potassium effluxes in Schwanniomyces occidentalis.”  Banuelos M.A.et.al.   9430707

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSINTNVAE KHSYKERVNT DASSLSADGS VEAHRLTIEQ VAKIFNTDII NGLSTSQANQ 
61:	TLKDFGANTL GDGDKISLTK IIAHQVCNAM ILVLIISMVI ALAIKDWISG GVIGFVVLIN 
121:	ISVGFVQEYK AEKTMGSLRS LSSPTARVTR NGDDTTIPAE EVVPGDIVHI KVGDTVPADL 
181:	RLIDLMNLET DEALLTGESL PITKNHLDVY DDYSVPIPVG DRLNLAYSSS VVSKGRGTGI 
241:	VIATALDTQI GQIAKSLRNN NSVIRKVDKS NGKPKKREYS KAFCGTIKDI FYNILGINVG 
301:	TPLQRKLSWL AIFLFWGCRY FCNYCNGIPK NRVNKEVAIY AICVALSMIP SALIVVLTIT 
361:	MAVGAQVMVM KHVIVRKLDS LEALGGINDI CSDKTGTLTQ GKMIARKTWI PNVGTFNVGN 
421:	SNDPFNPKAG EVSFVNLSPK FIEETDEEID FKQKLPSPFP ENFNNWLLTA TLANIATLNQ 
481:	SRDEETGELV WKAHGDATEI AIQVFTSRLN YGRDSLIENY EHLAEFPFDS SIKRMSAVYQ 
541:	SLQTNQIKVY TKGAVERVLN CCTHWYGHEE NDELYDNQQL KELTDDDKHL IESNMNALST 
601:	QGLRVLAFAT KDITNSSIDL SNRESIESNL IFQGLIGIYD PPRPETAGSV KSCHNAGINV 
661:	HMLTGDHPGT AKAIAQEVGI LPHNLYHYSE EVVKAMCMTA NEFDSLSDDE IDKLPVLPLV 
721:	IARCAPQTKV RMIEALHRRG KFVAMTGDGV NDSPSLKKAD VGIAMGLNGS DVAKDASDIV 
781:	LTDDNFASIL NAIEEGRRMS SNIQKFVLQL LAENVAQALY LMVGLAFIDD SGLSVFPLSP 
841:	VEVLWILVVT SCFPAMDLGQ ERASDDILEE SPNSTIFTWE VIIDMIVYGF WMAVCCLVCF 
901:	VIIVYGEGDP YLGVNCNKSS SSNSDVCELV FRGRSASFAT MTWCALILAW ECIHPYNSLF 
961:	YMRQDTDHPW WKQTVIDLWD NQFLFWSVAI GFISVFPVVY IPVINTKVFL HGPIGYEWGL 
1021:	AVGFSILFLA GSELWKWIKR IHKRKANKKA KNPEYELERS DPFKKYASFS RSNTMDRPEL 
1081:	MV