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3.A.3.9.7
P-type Ca2+ ATPase of 1041 aas and 12 TMSs.  Found to be essential for bloodstream-form Trypanosoma brucei through a genome-wide RNAi screen (Schmidt et al. 2018).

Accession Number:Q38CW7
Protein Name:Calcium motive P-type ATPase, putative
Length:1041
Molecular Weight:113976.00
Species:Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [185431]
Number of TMSs:10
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTGSGGREPI DVATGTAPAV DKGETIPTKY EPHNKWWSCD IPTTLSLVQL EDPSVGVPSS 
61:	DVSRRAAELG HNHIPLKGGP SALWILAQQF LNSITLILTI VMVISAVFED WAEFGVVLFL 
121:	ILFNALLGFY QEYSAEKSLE SLKAMTAGSA KVLRDGTVQV IFIDEVVVGD VIIIEQGSSV 
181:	PADCRIIESS GLEVDEALLT GEALPVVKHT NEIPDPGNSC ALGDRKNMVY RNTTVTQGRA 
241:	RAVVCAAGVD TEMGKLAARL ADGTGSGRTE LMRKLDLMMY ILFAVCLGLA LVVFAANRFK 
301:	FKRSTLSYAT AVAVAILPES LVAVVTVSMT FSVRNMARQR CIVRKLAVME VLGNVTDICS 
361:	DKTGTLTENK MVVKKALIGI DNELVVTGAP HERYGTFIRE EGEEHVNMLE VYETNKLAVE 
421:	FMRCAALCST TVLHPDSEDA DLLKGSGNPT EVAIQVMTWK ADAPRNKLEN QGWECIAEYP 
481:	FDSKIKRMST AWYNSETKSL YLCTKGAPER VIDLCTTKML ESGKLAPITD DDRQELTKKI 
541:	TSLASHGLRT ICFSMNASTV NEFPIPDDDT FQVTHPRETI EQSLTFLGIV GIYDPPRPES 
601:	RPSVIACQHA GIVVRMLTGD HAITARSIAT ILNIITAKDG EDPLKVLTGP EFDRIDMATI 
661:	EEWPDLPLVV GRCSPESKVK MIECLHKRGR TVAMTGDGFN DSPSIKFADV GCAMGSGTDV 
721:	TKGVADLIIT DDNFATIVKA VAEGRRISQN IRKFVLHLLS GNVSEVIALI CGLPIRYMGE 
781:	ALFVLSPVEI LWLNLCTSAP PATGLSLDPA SADVLLVPPH TAGLFTFELV TDFLVYGFWL 
841:	GGLALSAFVW IIYGINDGPK GENCNERTAV GCEMVWQARG TAFGILYFGL LVHSYTVRHP 
901:	RQSVIFMKWF DNPWIYGSVI VCSLLFFPIV YVPAIARNIF QHHSLTWHWG MMVPAVIIFV 
961:	GLCELHKIFK NCLFPVKRPV IDRSDEEEYR RFAVPGPDDD RDVESIAEDQ LRQSFVSAAG 
1021:	SIASGGRRRK GRRFGGKGGK M